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Matched Description: Lysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling … , proliferation, migration, and differentiation, vascular regulation, and cytokine release. Due to LPA's … . LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA … results in the dissociation of a Gα-GTP monomer and a Gβγ dimer from the receptor which allows both … , and myelination. This receptor can couple with the G proteins Gαi/o, Gαq/11, and Gα12/13. The Gαi/o

Matched Description: Glycogen storage disease, also called glycogenosis and dextrinosis, is a rare inborn error of … metabolism (IEM) and recessive disorder, which is caused by a defective glycogen synthase. Glycogen … synthase catalyzes the conversion of uridine diphosphate glucose into amylose and uridine 5'-diphosphate … which amylose is the substrate of 1,4-alpha-glucan-branching enzyme and glycogen debranching enzyme

Matched Description: . Superoxide dismutase takes superoxide radicals found in the cell and adds a hydrogen molecule to … them, forming hydrogen peroxide and oxygen, which are less harmful to the cell. This operon is … and gene region of the operon. This prevents translation from occurring, so the protein cannot be … the DNA and prevents transcription from occurring in various ways.

Matched Description: Glycogen storage disease, also called glycogenosis and dextrinosis, is a rare inborn error of … metabolism (IEM) and recessive disorder, which is caused by a defective glycogen synthase. Glycogen … synthase catalyzes the conversion of uridine diphosphate glucose into amylose and uridine 5'-diphosphate … which amylose is the substrate of 1,4-alpha-glucan-branching enzyme and glycogen debranching enzyme

Matched Description: Glycogen storage disease, also called glycogenosis and dextrinosis, is a rare inborn error of … metabolism (IEM) and recessive disorder, which is caused by a defective glycogen synthase. Glycogen … synthase catalyzes the conversion of uridine diphosphate glucose into amylose and uridine 5'-diphosphate … which amylose is the substrate of 1,4-alpha-glucan-branching enzyme and glycogen debranching enzyme

Matched Description: Globoid Cell Leukodistrophy (GLD), also called Krabbe disease and galactosylceramide lipidosis, is … population and a worldwide incidence of 1/100,000-1/250,000 live births. GLD is an autosomal recessive … is a lysosomal protein that hydrolyzes the galactose ester bonds of ceramides and ceramide … derivatives including galactocerebroside, galactosylsphingosine (psychosine), lactosylceramide, and … catabolism (via the removal of galactose) of galactosylceramide, a major lipid in myelin, kidney, and

Matched Description: chronic hepatitis B. Adefovir dipivoxil is taken up into the liver cell and is cleaved into adefovir … by intracellular esterases. Adefovir is subsequently phosphorylated first by adenylate kinases and … analogue of deoxyadenosine triphosphate (dATP) and competes with dATP for binding to the viral DNA … polymerase and subsequent incorporation into the growing DNA strand. Once incorporated into the DNA

Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate

Matched Description: different phosphoinositides have been identified in mammals, each distinguished by the number and/or … cell, such as actin cytoskeletal reorganization, membrane transport, and cell proliferation. They … may also affect protein localization, aggregation, and activity by acting as secondary messengers. The … signals means that their synthesis and metabolism must be tightly regulated. Synthesis begins with the … a number of specific phosphoinositide kinases and phosphatases, which add (kinase) and remove

Matched Proteins: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Matched Description: Taurine and hypotaurine are aminosulfinic acids. Taurine has many physiological functions as … neuromodulators, membrane stabilizers, facilitator of ion transport and aiding auditory transduction … . Hypotaurine has roles such as antioxidant and a protective agent. Taurine and hypotaurine are … synthesized from L-cysteine. L-Cysteine is involved in cyanoacid metabolism and glutathione metabolism. L … -Cysteine goes through redox reactions, elimination reactions and other metabolism pathways to