SMP0385919
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Proline Metabolism
Serratia marcescens subsp. marcescens Db11
Matched Description: , an NADP and a L-glutamic gamma-semialdehyde. L-glutamic gamma-semialdehyde is dehydrated … spontaneously, resulting in a release of water,hydrogen ion and 1-Pyrroline-5-carboxylic acid. The latter … -proline. L-proline works as a repressor of the pyrroline-5-carboxylate reductase enzyme and glutamate 5 … -kinase. Three genetic loci, proA, proB and proC control the biosynthesis of L-proline in E … the antagonistic nucleophilic and aqueous environment found in the cell. Finally, NADPH-dependent
Matched Proteins: Glutamate and aspartate transporter subunit
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SMP0445832
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Secondary Metabolites: Glyoxylate Cycle
Megasphaera elsdenii DSM 20460
Matched Description: The glyoxylate cycle starts with the interaction of Acetyl-Coa with a water molecule and Oxalacetic … acid interact through a Citrate synthase resulting in a release of a coenzyme a and citric acid … molecule and cis-Aconitic acid. The cis-Aconitic acid is then hydrated in an reversible reaction through … reversible reaction through isocitrate lyase resulting in the release of a succinic acid and a glyoxylic … acid. The glyoxylic acid then reacts in a reversible reaction with an acetyl-coa, and a water
Matched Proteins: Lactoylglutathione lyase and related lyases
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SMP0000659
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Timolol Action Pathway
Homo sapiens
Matched Description: relieves symptoms such as tachycardia, vascular headaches, hypertension, angina and tremors. Timolol, much … kinase catalytic subunit alpha activates outage-dependent L-type calcium channel subunit alpha 1C and 2 … transporting calcium into the myocyte from the the sarcoplasmic reticulum. The calcium and calmodulin then … muscle, results in a muscle contraction. Then in the cell membrane we have PIP2(16:0/20:3(8Z,11Z … ,14Z)) catalyzing into DG(14:0/14:1(9Z)/0:0) and inositol 1,4,5-triphosphate with the help of the
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SMP0120960
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Stat3 Signaling Pathway
Rattus norvegicus
Matched Description: by some of the cells in the immune system, and are vital to signalling pathways in the body of … find tyrosine-kinases that are associated to the receptor, including JAK and Src when it is time for … phosphorylation cascade. This means that STAT3 is now activated, and its compounds disconnect from the … receptor site, and relocate to the nucleus. Once there, the compounds bind to DNA response elements, and … take part in many processes against target genes, such as apoptosis and cell proliferation, regulating their transcription.
Matched Proteins: Signal transducer and activator of transcription 3
Gene Regulatory
Cytokine Signaling
Cellular Response
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SMP0452060
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Secondary Metabolites: Cysteine Biosynthesis from Serine
Bacteroides xylanisolvens XB1A
Matched Description: -phosphoglycerate dehydrogenase / α-ketoglutarate reductase resulting in an NADH, a hydrogen ion and a … aminotransferase / phosphohydroxythreonine aminotransferase resulting in a oxoglutaric acid and a DL-D … phosphatase resulting in a phosphate and an L-serine. The L-serine interacts with an acetyl-coa through a … serine acetyltransferase resulting in a release of a Coenzyme A and a O-Acetylserine. The O … -acetylserine then interacts with a hydrogen sulfide through a O-acetylserine sulfhydrylase A resulting in an acetic acid, a hydrogen ion and an L-cysteine
Matched Proteins: Lactate dehydrogenase and related dehydrogenases
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SMP0449415
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Secondary Metabolites: Glyoxylate Cycle
Providencia stuartii ATCC 25827
Matched Description: The glyoxylate cycle starts with the interaction of Acetyl-Coa with a water molecule and Oxalacetic … acid interact through a Citrate synthase resulting in a release of a coenzyme a and citric acid … molecule and cis-Aconitic acid. The cis-Aconitic acid is then hydrated in an reversible reaction through … reversible reaction through isocitrate lyase resulting in the release of a succinic acid and a glyoxylic … acid. The glyoxylic acid then reacts in a reversible reaction with an acetyl-coa, and a water
Matched Proteins: Translocation and assembly module TamB
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SMP0376980
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Fatty Acid Oxidation (Laurate)
Bacteroides xylanisolvens XB1A
Matched Description: because they are anhydrous and can be reduced. Fatty acids are good sources of energy as they yield … under anaerobic and aerobic conditions. Enzymes of this pathway can process short and long chain
Matched Proteins: Predicted dehydrogenases and related proteins
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SMP0002239
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Operon: dnaAN-recF
Escherichia coli
Matched Description: and replication. The operon can be activated by the binding of HTH-type transcriptional regulator … the number of DnaA-ATP complexes bound. When cells have grown, DnaA is produced and can accumulate … operon, recF, encodes the DNA replication and repair protein RecF, a protein required for DNA replication, as well as recombination.
Matched Proteins: DNA replication and repair protein RecF
Gene Regulatory
Cellular Response
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SMP0452523
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Secondary Metabolites: Shikimate Pathway
Methylococcus capsulatus
Matched Proteins: ATP-dependent helicase Lhr and Lhr-like helicase
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SMP0120936
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Stat3 Signaling Pathway
Bos taurus
Matched Description: by some of the cells in the immune system, and are vital to signalling pathways in the body of … find tyrosine-kinases that are associated to the receptor, including JAK and Src when it is time for … phosphorylation cascade. This means that STAT3 is now activated, and its compounds disconnect from the … receptor site, and relocate to the nucleus. Once there, the compounds bind to DNA response elements, and … take part in many processes against target genes, such as apoptosis and cell proliferation, regulating their transcription.
Matched Proteins: Signal transducer and activator of transcription 3
Gene Regulatory
Cytokine Signaling
Cellular Response
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