SMP0060208
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Terfenadine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0056661
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Chlorphenamine H1-Antihistamine Action
Homo sapiens
Matched Description: -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to … conjunctivitis, and urticaria. Reducing the activity of the NF-κB immune response transcription factor through … the phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen … presentation and the expression of pro-inflammatory cytokines, cell adhesion molecules, and … -brain barrier and cause sedation and other adverse central nervous system (CNS) effects (e.g
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SMP0060170
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Bilastine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0057583
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Mepyramine H1-Antihistamine Action
Homo sapiens
Matched Description: interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. Reducing the activity of the NF-κB immune response transcription factor through the … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen … presentation and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic … barrier and cause sedation and other adverse central nervous system (CNS) effects (e.g. nervousness
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SMP0058732
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Histapyrrodine H1-Antihistamine Action
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0057585
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Chloropyramine H1-Antihistamine Action
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0059716
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Isothipendyl H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0175124
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Desloratadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0175122
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Loratadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0175078
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Azatadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the activity of the NF … -κB immune response transcription factor through the phospholipase C and the phosphatidylinositol … (PIP2) signalling pathways also decreases antigen presentation and the expression of pro-inflammatory … cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering calcium ion
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