SMP0175122
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Loratadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0175078
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Azatadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the activity of the NF … -κB immune response transcription factor through the phospholipase C and the phosphatidylinositol … (PIP2) signalling pathways also decreases antigen presentation and the expression of pro-inflammatory … cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering calcium ion
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SMP0175073
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Dexbrompheniramine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … and cause sedation and other adverse central nervous system (CNS) effects (e.g. nervousness and
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SMP0401755
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NAD Salvage
Bacteroides clarus YIT 12056
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0401822
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NAD Salvage
Bacteroides xylanisolvens XB1A
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0402239
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NAD Salvage
Bartonella quintana str. Toulouse
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0407616
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NAD Salvage
Weissella cibaria KACC 11862
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0407615
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NAD Salvage
[Clostridium] symbiosum ATCC 14940
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0407472
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NAD Salvage
Vibrio fluvialis PG41
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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SMP0407748
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NAD Salvage
Subdoligranulum variabile DSM 15176
Matched Description: NAD molecules have a relatively short half-life. NAD can be degraded by enzymes, and the degraded … degraded NAD products such as nicotinamide and nicotinamide D-ribonucleotide. NAD salvage cycles can … release of hydrogen ion, AMP and beta-nicotinamide D-ribonucleotide. This enzyme can either interact … spontaneously with water resulting in the release of D-ribofuranose 5-phosphate, hydrogen ion and … amidohydrolase resulting in ammonium, and Nicotinate beta-D-ribonucleotide. Also it can interact with
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