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Matched Description: The biosynthesis of phosphoribosyl pyrophosphate begins as a product of the pentose phosphate and D … hydrogen ion, ADP and a ribose 1,5-biphosphate. Ribose 1,5-biphosphate is then phosphorylated through a … ribose 1,5-bisphosphokinase resulting in the release of ADP and phosphoribosyl pyrophosphate … . Alternatively pentose phosphate and D-ribose 5-phosphate's interaction can be phosphorylated through … an ATP driven ribose-phosphate diphosphokinase resulting in a release of a hydrogen ion, an AMP and a

Matched Description: The BCR signalling pathway is a pathway that plays a vital role in the development and all other … synapses, through a number of processes including cell spreading and receptor transport. After these … have been performed, endocytosis and antigen-presentation occur. B-cells manipulate the dynamic of … BCR-antigen bonds. They group and spread the antigen, increasing the relation with BCR, which creates … sensitivity. The two main functions of the BCR pathway is to signal transduction, and the second is

Matched Description: chemical group, and 10 refers to the isoprenyl chemical subunits. Ubiquinone is a carrier of hydrogen … atoms (protons plus electrons) and functions as an ubiquitous coenzyme in redox reactions, where it … is first reduced to the enzyme-bound intermediate radical semiquinone and in a second reduction to … -chondrial membrane and in other membranes such as the endoplasmic reticulum, Golgi vesicles, lysosomes and

Matched Description: is catalyzed by CYP3A4 and CYP2C19. N-desmethylvenlafaxine is a weaker serotonin and norepinephrine … inhibitor) and N-desmethylvenlafaxine are further metabolized by CYP2C19, CYP2D6 and/or CYP3A4 to a minor … resistance protein 1 and ATP-binding cassette sub-family G member 2.

Matched Description: NADH dehydrogenase and nitrate reductase can form the anaerobic respiratory chain that can be used … . In E. coli K-12, NDH-I and NDH-II is the two energy conserving NADH dehydrogenases that do not … , there are also two energy conserving (H+/e- = 1) nitrate reductases (nitrate reductase A (NRA) and … anaerobiosis. Nitrate and hydrogen atom will be catalyzed to form nitrite and water during nitrate reduction.

Matched Description: Thioredoxins are a class of proteins that are used in redox reactions, and are found in all living … for growth, photosynthesis, flowering and seed formation. In E. coli, thioredoxins catalyze a number … of redox reactions, and are important in stress response, as well as other functions. In this pathway … , acts as the oxidizing agent and converts an oxidized electron acceptor into a reduced electron … acceptor. This then produces oxidized thioredoxin, which can be further reduced and reused in other redox reactions.

Matched Description: geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is … of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of both D1 and D2 dopamine … receptors. Flupentixol is an antipsychotic agent with anxiolytic and mild sedative actions. It exerts … weak anticholinergic and adrenergic effects. It possesses antiemetic actions. As flupentixol works … antagonist at both dopamine D1 and D2 receptors with equal affinities.

Matched Description: Doxylamine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms … such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting … in pregnancy. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and … rhinitis, allergic conjunctivitis, and urticaria. Wakefulness is regulated by histamine in the

Matched Description: fungal infections Candidemia and other forms of Candida infections (intra-abdominal abscess, and … peritonitis), Aspergillus infections, and esophageal candidiasis. Also considered an alternative treatment … , invasive aspergillosis, and oropharyngeal candidiasis. As an echinocandin antifungal, Anidulafungin … synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, which ultimately leads to osmotic instability and cell death.

Matched Description: acute uncomplicated malaria caused by Plasmodium falciparum and unidentified Plasmodium species … onset of action and is rapidly cleared from the body. It is thus thought to provide rapid symptomatic … relief by reducing the number of malarial parasites. Lumefantrine has a much longer half life and is … β-hematin by forming a complex with hemin and inhibits nucleic acid and protein synthesis, as well as causing the accumulation of toxic heme.