SMP0404329
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Isoleucine Biosynthesis
Escherichia coli 042
Matched Description: -threonine interacts with threonine dehydratase biosynthetic releasing water, a hydrogen ion and (2Z)-2 … -aminobut-2-enoate. The latter is isomerized into a 2-iminobutanoate which interacts with water and a … hydrogen ion spontaneously, resulting in the release of ammonium and 2-ketobutyric acid. 2-ketobutyric … acid reacts with pyruvic acid and hydrogen ions through an acetohydroxybutanoate synthase … / acetolactate synthase 2 resulting in carbon dioxide and (S)-2-Aceto-2-hydroxybutanoic acid. (S)-2-Aceto-2
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SMP0396334
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Isoleucine Biosynthesis
Escherichia coli (strain MS 21-1)
Matched Description: -threonine interacts with threonine dehydratase biosynthetic releasing water, a hydrogen ion and (2Z)-2 … -aminobut-2-enoate. The latter is isomerized into a 2-iminobutanoate which interacts with water and a … hydrogen ion spontaneously, resulting in the release of ammonium and 2-ketobutyric acid. 2-ketobutyric … acid reacts with pyruvic acid and hydrogen ions through an acetohydroxybutanoate synthase … / acetolactate synthase 2 resulting in carbon dioxide and (S)-2-Aceto-2-hydroxybutanoic acid. (S)-2-Aceto-2
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SMP0403662
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Isoleucine Biosynthesis
Escherichia coli E24377A
Matched Description: -threonine interacts with threonine dehydratase biosynthetic releasing water, a hydrogen ion and (2Z)-2 … -aminobut-2-enoate. The latter is isomerized into a 2-iminobutanoate which interacts with water and a … hydrogen ion spontaneously, resulting in the release of ammonium and 2-ketobutyric acid. 2-ketobutyric … acid reacts with pyruvic acid and hydrogen ions through an acetohydroxybutanoate synthase … / acetolactate synthase 2 resulting in carbon dioxide and (S)-2-Aceto-2-hydroxybutanoic acid. (S)-2-Aceto-2
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SMP0397593
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Isoleucine Biosynthesis
Megasphaera elsdenii DSM 20460
Matched Description: -threonine interacts with threonine dehydratase biosynthetic releasing water, a hydrogen ion and (2Z)-2 … -aminobut-2-enoate. The latter is isomerized into a 2-iminobutanoate which interacts with water and a … hydrogen ion spontaneously, resulting in the release of ammonium and 2-ketobutyric acid. 2-ketobutyric … acid reacts with pyruvic acid and hydrogen ions through an acetohydroxybutanoate synthase … / acetolactate synthase 2 resulting in carbon dioxide and (S)-2-Aceto-2-hydroxybutanoic acid. (S)-2-Aceto-2
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SMP0127025
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Gi Serotonergic Vasoconstriction
Rattus norvegicus
Matched Description: molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli … to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). When they are … bound to GTP, they are 'on', and, when they are bound to GDP, they are 'off'. G proteins belong to … to a domain of the GPCR located outside the cell, and an intracellular GPCR domain then in turn … protein-coupled receptors and G proteins working together transmit signals from many hormones
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SMP0127026
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Gi Serotonergic Vasoconstriction
Mus musculus
Matched Description: molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli … to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). When they are … bound to GTP, they are 'on', and, when they are bound to GDP, they are 'off'. G proteins belong to … to a domain of the GPCR located outside the cell, and an intracellular GPCR domain then in turn … protein-coupled receptors and G proteins working together transmit signals from many hormones
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SMP0126490
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Cladribine Action Pathway
Homo sapiens
Matched Description: in the treatment of active hairy cell leukemia and relapsing forms of Multiple sclerosis (MS). This … lymphoma, and cutaneous T-cell lymphoma. This molecule is a synthetic purine nucleoside, it is … nucleotidecladribine triphosphate and this metabolite is incorporated into the DNA of T and B cells … . This results in DNA strand breakage and inhibition of the DNA synthesis and/or repair. This drug has … the other antimetabolite drugs. The drug causes the lymphocytes to stay and accumulate in the G1/S
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SMP0002060
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Secondary Metabolites: Enterobacterial Common Antigen Biosynthesis 3
Escherichia coli
Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6
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SMP0121316
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Sulfur Metabolism (Butanesulfonate)
Pseudomonas aeruginosa
Matched Description: an ATP hydrolysis and dehydrogenation reaction by the adenylyl-sulfate kinase. Phoaphoadenosine … phosphosulfate is finally dehydrogenated and converted to sulfite by phosphoadenosine phosphosulfate … reductase. This reaction requires magnesium, and adenosine 3',5'-diphosphate is the bi-product. A … conversion of sulfite to hydrogen sulfide through hygrogenation and the deoxygenation of sulfite to form a … water molecule. The reaction is catalyzed by the sulfite reductase [NADPH] flavoprotein alpha and
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SMP0130948
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Norepinephrine Neurological
Rattus norvegicus
Matched Description: catecholamine family that functions in the brain and body as both a hormone and neurotransmitter … . The name "noradrenaline" (from Latin ad, "near", and ren, "kidney") is more commonly used in the … United Kingdom, whereas "norepinephrine" (from Ancient Greek ἐπῐ́ (epí), "upon", and νεφρός (nephrós … of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest … during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or
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