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Matched Description: reduction of the potassium conductance and, in consequence, the depolarization of the membrane. This … . Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. This drug class is … also associated with weight gain and hypoglycemia, they require a consistent food intake to decrease this risk.

Matched Description: targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced … by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2 … ) agonists, which are used to treat high blood pressure and asthma, for example. The α2, on the other … heterotrimeric G protein, composed of three subunits: a Gα protein such as Giα, and a complex of two … tightly linked proteins called Gβ and Gγ in a Gβγ complex. When not stimulated by a receptor, Gα is

Matched Description: . The perflutren lipid microspheres exhibit lower acoustic impedance than blood and enhance the … infused into the body. When exposed to ultrasound waves, the microspheres resonate and "echo" strong … signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and

Matched Description: smooth muscle cells, enterochromaffin cells, and myenteric plexus. Its activation produces the release of … release of acetylcholine and further contraction of the muscle layer of the colon and relaxation of

Matched Description: Thioguanine is a purine antimetabolite prodrug closely related to mercaptopurine and similarly … . Thioguanine exerts cytotoxic effects via incorporation of thiodeoxyguanosine triphosphate into DNA and … thioguanosine triphosphate into RNA and inhibition of Ras-related C3 botulinum toxin substrate 1

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.