SMP0100159
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Phosphatidylcholine/Phosphatidylethanolamine Biosynthesis PC(16:0/18:1(9Z)) | PE(16:0/18:1(9Z))
Caenorhabditis elegans
Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, they are
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SMP0100171
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Phosphatidylcholine/Phosphatidylethanolamine Biosynthesis PC(16:1(9Z)/i-17:0) | PE(16:1(9Z)/i-17:0)
Caenorhabditis elegans
Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, they are
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SMP0100186
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Phosphatidylcholine/Phosphatidylethanolamine Biosynthesis PC(i-17:0/18:1(9Z)) | PE(i-17:0/18:1(9Z))
Caenorhabditis elegans
Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. In the … most abundant phospholipid in eukaryotic cell membranes, and contrary to phosphatidylcholine, they are
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SMP0000486
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DOPA-Responsive Dystonia
Homo sapiens
Matched Description: DOPA-Responsive Dystonia is a condition in which the muscles contract, experience tremors and … of this condition are dystonia in the legs, and clubfeet. The cause of this condition is usually a … and serotonin, and the processing of quite a few amino acids, The mutation on GCH1 causes GTP … why patients with DOPA-responive dystonia experience tremors and movement problems.
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SMP0123129
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Dobutamine Action Pathway (New)
Homo sapiens
Matched Description: release of endogenous norepinephrine. Instead, it acts as a cardiac stimulant and stimulates … contractility) is greater than its chronotropic effect, so dobutamine is used for acute heart failure and … -1 adrenoceptors to increase intracellular via G protein-mediated cyclic AMP and protein kinase A … and through L-type calcium channels. Dobutamine can also bind to beta-2 or alpha receptors, though … exerts mild chronotropic, arrhythmogenic, hypertensive, and vasodilatory effects.
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SMP0122858
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Clindamycin Anti-Bacterial Action Pathway
Homo sapiens
Matched Description: infections including and not limited to bone or joint infections, strep throat, ear infections, pneumonia … and acne. It mainly targets anaerobic bacteria, gram-positive cocci and bacilli and gram-negative … as clindamycin can also just be administered by itself and taken up in transporters.
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SMP0126429
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Milnacipran SNRI - Norepinephrine reuptake Inhibition Action Pathway
Homo sapiens
Matched Description: Milnacipran is a serotonin and norepinephrine reuptake inhibitor (SNRI). It is used in the … pain and diabetic peripheral neuropathy. It is generally believed that 5HT and NE participate in … the brain and spinal cord. Although the specific mechanism of action remains unclear, some studies … nociceptors, by direct alpha-2-adrenergic action on pain-relay neurons, and by alpha-1-adrenoceptor
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SMP0401570
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Mannose Metabolism
Aeromonas media WS
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0401471
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Mannose Metabolism
Escherichia coli (strain K12 / MC4100 / BW2952)
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0410569
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Mannose Metabolism
Escherichia coli K-12
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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