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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 319406 results

SMP0120905

Pw122168 View Pathway
Protein

Ubiquitin–Proteasome Pathway

Mus musculus

  • Matched Description: effects in many other pathways and processes. This pathway uses 2 distinct steps. The first step is that … . This pathway is important for DNA repair, regulating the amount of proteins, and the creation of antigen-peptide.
  • Matched Proteins: STIP1 homology and U box-containing protein 1

  • Transport/Degradation
    Cellular Response

    SMP0407945

    Missing View Pathway
    Metabolite

    Lipopolysaccharide Biosynthesis

    Halococcus morrhuae DSM 1307

  • Matched Description: either the fructose 6-phosphate produced by glycolysis and pyruvate dehydrogenase or obtained from the … and a glucosamine 6-phosphate. The latter compound is isomerized through a phosphoglucosamine mutase … through a bifunctional protein glmU resulting in a Coenzyme A, hydrogen ion and N-acetyl-glucosamine 1 … -phosphate. The latter interacts with UTP and hydrogen ion through the bifunctional protein glmU … resulting in a pyrophosphate and a UDP-N-acetylglucosamine. UDP-N-acetylglucosamine iinteracts with (3R)-3
  • Matched Proteins: Xanthine and Co dehydrogenase maturation factor

  • Metabolic

    SMP0422563

    Missing View Pathway
    Metabolite

    Oxidative Phosphorylation

    Odoribacter laneus YIT 12061

  • Matched Description: acid, resulting in a fumaric acid and ubiquinol. Ubiquinone interacts with succinic acid through a … cofactors, ferroheme b, 2FE-2S, FAD, and 3Fe-4S iron-sulfur cluster. Then 2 ubiquinol interact with … oxygen and 4 hydrogen ion through a cytochrome bd-I terminal oxidase resulting in a 4 hydrogen ion … transferred into the periplasmic space, 2 water returned into the cytoplasm and 2 ubiquinone, which … and 4 hydrogen ion through a cytochrome bd-II terminal oxidase resulting in a 4 hydrogen ion
  • Matched Proteins: Succinate dehydrogenase and fumarate reductase iron-sulfur protein

  • Metabolic

    SMP0107992

    Pw109033 View Pathway
    Metabolite

    Histamine H1 Receptor Activation

    Mus musculus

  • Matched Description: -like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3, and H4 … . Histamine receptor H1 belongs to the family of G-protein-coupled receptors (GPCRs), and it is … expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous … system. It is linked to an intracellular G-protein (Gαq) that activates phospholipase C and the … release and expression of the NF-κB immune response transcription factor. H1-antihistamines inactivate

  • Signaling

    SMP0126102

    Pw127681 View Pathway
    Metabolite

    Pirbuterol Action Pathway

    Homo sapiens

  • Matched Description: is used as a bronchodilator for the treatment of asthma and relief from bronchospasm. The result of … taking this drug is relaxation of the bronchial smooth muscles causing bronchodilaton and increased … airflow. Once pirbuterol is administered and it binds to the beta-2 adrenergic receptor, the G … protein signalling cascade begins. The alpha and beta/gamma subunits of the G protein separate and GDP … and inhibits MLCK through decreased calcium levels causing muscle relaxation. PKA can phosphorylate

  • Drug Action

    SMP0126088

    Pw127667 View Pathway
    Metabolite

    Arformoterol Action Pathway

    Homo sapiens

  • Matched Description: and chronic bronchitis. It accomplishes this by upon inhalation of the drug by relaxing smooth … muscles in the airways to improve breathing. It can be found under the brand name Brovana, and it has a … 2 fold greater potency than racemic formoterol. Once arformoterol is administered and it binds to … the beta-2 adrenergic receptor, the G protein signalling cascade begins. The alpha and beta/gamma … subunits of the G protein separate and GDP is replaced with GTP on the alpha subunit. This alpha subunit

  • Drug Action

    SMP0174954

    Pw176640 View Pathway
    Metabolite

    Dexchlorpheniramine maleate H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Dexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and … vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax

  • Drug Action

    SMP0126086

    Pw127665 View Pathway
    Metabolite

    Formoterol Action Pathway

    Homo sapiens

  • Matched Description: Formoterol is a long acting beta-2 adrenergic receptor agonist that is used as a bronchodilator and … to manage asthma and COPD. It can be used as well for prophylaxis against exercise induced … bronchospasm. This drug is inhaled and can be recognized under the brand names Bevespi, Breyna, Duaklir … , Foradil, Oxeze, Zenhale, and Symbicort. Formoterol both has a rapid onset and a long duration of action … muscles and opening of the airways through its binding to the beta-2 adrenergic receptors which causes G

  • Drug Action

    SMP0124744

    Pw126232 View Pathway
    Metabolite

    Betaine Drug Metabolism

    Homo sapiens

  • Matched Description: Betaine is obtained from foods such as wheat, shellfish, spinach, and beets. In the intestine … ). The toxicity of betaine is due to the formation of TMA and its metabolism to Trimethylamine N-oxide … microbe, then TMA then enters the bloodstream and is transported to the liver where dimethylaniline … the heart, kidney and vascular system by contributing to cardiovascular disease, atherosclerosis, endothelial dysfunction and kidney disease.

  • Metabolic

    SMP0126638

    Pw128240 View Pathway
    Metabolite

    Anistreplase Action Pathway (new)

    Homo sapiens

  • Matched Description: such as myocardial infarction and pulmonary emboli. It is administered intravenously and travels … fibrin matrix of the blood clot breaking it down into degradation products. Due to its anticoagulant and … antiplatelet activity, avoid herbs and supplements with similar activity such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba.

  • Drug Action