SMP0011732
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Cardiolipin Biosynthesis CL(16:0/18:0/18:0/20:1(13Z))
Saccharomyces cerevisiae
Matched Description: reacts with glycerol-3-phosphate O-acyltransferase resulting in the release of 1-acyl-sn-glycerol 3 … the removal of an acyl chain to form 1-monolysocardiolipin (1-MLCL) via the lipase Cld1p. This is
Matched Compounds: CDP-DG(18:0/20:1(13Z)) … CL(16:0/18:0/18:0/20:1(13Z)) … MLCL(0:0/18:0/18:0/20:1(13Z))
Matched Proteins: Glycerol-3-phosphate O-acyltransferase 1 … Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase … Lysophosphatidic acid:oleoyl-CoA acyltransferase 1 … Maintenance of mitochondrial morphology protein 1 … Mitochondrial distribution and morphology protein 10
Matched Compound Synonyms: (r)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide inner salt … (r)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide hydroxide inner salt … 1-hydroxy-3-(phosphonooxy)acetone … D-glycerol 1-phosphate … D-glycerol 1-phosphoric acid
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SMP0028533
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Cardiolipin Biosynthesis CL(18:1(11Z)/18:0/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Homo sapiens
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(18:1(11Z)/0:0) … PA(18:1(11Z)/18:0) … CDP-DG(18:1(11Z)/18:0) … PGP(18:1(11Z)/18:0) … PG(18:1(11Z)/18:0)
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon … Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 5 … 1-AGPAT 5 … 1-acylglycerol-3-phosphate O-acyltransferase 5 … PGP synthase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0027520
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Cardiolipin Biosynthesis CL(16:1(9Z)/16:0/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Homo sapiens
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/16:0) … CDP-DG(16:1(9Z)/16:0) … PGP(16:1(9Z)/16:0) … PG(16:1(9Z)/16:0)
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon … Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 5 … 1-AGPAT 5 … 1-acylglycerol-3-phosphate O-acyltransferase 5 … PGP synthase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0087238
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Steroidogenesis
Bos taurus
Matched Proteins: Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-13-carbaldehyde … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide
Matched EC Numbers: 1.-.-.-
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SMP0077718
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Cardiolipin Biosynthesis CL(16:1(9Z)/16:0/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Bos taurus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/16:0) … CDP-DG(16:1(9Z)/16:0) … PGP(16:1(9Z)/16:0) … PG(16:1(9Z)/16:0)
Matched Proteins: 1-Acyl-sn-glycerol-3-phosphate acyltransferase delta … Protein tyrosine phosphatase, mitochondrial 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0093923
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Cardiolipin Biosynthesis CL(18:1(11Z)/16:0/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(18:1(11Z)/0:0) … PA(18:1(11Z)/16:0) … CDP-DG(18:1(11Z)/16:0) … PGP(18:1(11Z)/16:0) … PG(18:1(11Z)/16:0)
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0094003
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Cardiolipin Biosynthesis CL(18:1(11Z)/18:0/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(18:1(11Z)/0:0) … PA(18:1(11Z)/18:0) … CDP-DG(18:1(11Z)/18:0) … PGP(18:1(11Z)/18:0) … PG(18:1(11Z)/18:0)
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0092986
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Cardiolipin Biosynthesis CL(16:1(9Z)/16:0/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/16:0) … CDP-DG(16:1(9Z)/16:0) … PGP(16:1(9Z)/16:0) … PG(16:1(9Z)/16:0)
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0000717
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Apparent Mineralocorticoid Excess Syndrome
Homo sapiens
Matched Description: levels. Antihypertensive agents are also effective. It is estimated that AME affects less than 1 in
Matched Proteins: Aldo-keto reductase family 1 member C4 … Corticosteroid 11-beta-dehydrogenase isozyme 1 … 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
Matched Protein Synonyms: Aldo-keto reductase family 1 member D1 … 11-beta-hydroxysteroid dehydrogenase 1 … Aldo-keto reductase family 1 member D1 … Aldo-keto reductase family 1 member D1 … Aldo-keto reductase family 1 member D1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-13-carbaldehyde … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide
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SMP0120868
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Apparent Mineralocorticoid Excess Syndrome
Rattus norvegicus
Matched Description: levels. Antihypertensive agents are also effective. It is estimated that AME affects less than 1 in
Matched Proteins: Corticosteroid 11-beta-dehydrogenase isozyme 1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-13-carbaldehyde … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide
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