SMP0058785
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Diphenhydramine H1-Antihistamine Action
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0058797
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Carbinoxamine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0059720
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Mequitazine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0059738
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Oxomemazine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0060224
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Levocabastine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0060230
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Mizolastine H1-Antihistamine Action
Homo sapiens
Matched Description: interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen … presentation and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic … and cause sedation and other adverse central nervous system (CNS) effects (e.g. nervousness and
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SMP0060235
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Rupatadine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0060742
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Thiazinamium H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0061040
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Emedastine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0062623
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Latrepirdine H1-Antihistamine Action
Homo sapiens
Matched Description: of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of pro … -inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering
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