SMP0000661
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Epinephrine Action Pathway
Homo sapiens
Matched Description: Epinephrine can be derived from phenylalanine and tyrosine and it is an active sympathomimetic … hormone that can be secreted from adrenal medulla. Epinephrine can stimulate alpha- and beta … - adrenergic systems by binding on alpha-1 and beta-1 adrenergic receptors to make gastrointestinal relaxation … , constrict arterioles in skin and gut while dilating arterioles in leg muscles, increase glycogen … hydrolysis to glucose in liver to raise up blood sugar level and breaking down lipids in adipocytes
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SMP0000745
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Stavudine Action Pathway
Homo sapiens
Matched Description: with the retrovirus designated as human immunodeficiency virus (HIV-l). Stavudine is a potent and … selective inhibitor of HIV-replication and of cytopathic effects in a variety of mammalian cells, and is … enzymes to the mono-, di-, and triphosphates and is ultimately incorporated into the DNA of growing … treated with Stavudine, due to terminal addition of Stavudine to DNA and the resultant chain termination.
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SMP0000291
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Doxycycline Action Pathway
Homo sapiens
Matched Description: lipophilic and can diffuse through the lipid bilayer of bacteria. Doxycycline reversibly binds to the … bacterial 30S ribosomal subunit and to a lesser extent the 50S subunit, blocking the binding of … and hence cell growth.
Doxycycline may be used to treat treat non-gonococcal urethritis and … cervicitis, adult periodontitis, rosacea, inflammatory acne vulgaris and syphilis in patients allergic to … penicillin. It may also be used as prophylaxis against chloroquine-resistant and/or mefloquine
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SMP0126759
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Linezolid Action Pathway
Homo sapiens
Matched Description: Linezolid is a synthetic antibiotic, also known as Zyvox and Zyvoxam used to treat gram-positive … bacteria. Linezolid is absorbed after oral administration and travels to the bacterial cell, it binds … reproduction. Linezolid is metabolized to aminoethoxyacetic acid and hydroxyethyl glycine and … metabolites through oxidation. When taking linezolid foods and supplements containing tyramine such as … cheese, red wine, fava beans, pickled foods, cured foods and alcoholic beverages.
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SMP0497682
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Escherichia coli (strain B / BL21-DE3)
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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SMP0658831
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Enterobactin Biosynthesis
Pseudomonas aeruginosa
Matched Description: and Salmonella typhimurium. Under iron-deficient condtion, enterobactin can be synthesized and … biosynthesis, and it can be obtained from chorismate biosynthesis pathway. Isochorismate synthase catalyzes … chorismate to form isochorismate, and further breaking down to form (2S,3S)-2,3-dihydroxy-2,3 … -dihydrobenzoate and pyruvic acid by same synthase enzyme. (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate is … synthesis of enterobactin is catalyzed from 2,3-dihydroxybenzoate and L-serine.
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SMP0501455
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Parabacteroides johnsonii DSM 18315
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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SMP0646213
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Brevundimonas bacteroides DSM 4726
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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SMP0509824
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Escherichia coli O157:H7
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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SMP0511052
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Xanthomonas campestris
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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