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Matched Description: lipoproteins, peptidoglycans, lipotechoic acids, and mannan. TLR3 recognizes viral double-stranded … RNA, small interfering RNAsa, and self-RNAs. TLR4 recognizes lipopolysaccharides. TLR7 recognizes … single-stranded RNA. TLR9 recognizes bacterial and viral DNA with unmethylated CpG-DNA motifs. TLRs … are synthesized in the endoplasmic reticulum, moved to the Golgi, and then recruited to the cell … . MYD88 is recruited by all TLRs. Adaptor TIRAP recruits MYD88 to cell surface TLRs, including TLR2 and

Matched Description: the brand names Zonegran and Zonisade and is administered as an oral capsule. Zonisamide is a … extensor component of tonic convulsion, restricts the spread of focal seizures and prevents the … be due to its effects on sodium and calcium channels. Zonisamide blocks sodium channels and reduces … voltage-dependent, transient inward currents, stabilizing neuronal membranes and suppressing neuronal … , release, and degradation of neurotransmitters, such as glutamate. The use of zonisamide may lead to

Matched Description: Viomycin is an antibiotic used to treat Mycobacterium tuberculosis and binds to the ribosome … 44 of the small ribosomal subunit and helix 69 of the large ribosomal subunit which stops tRNA from … binding to the A site and the addition of amino acids to a polypeptide chain.

Matched Description: metabolite aripiprazole, and to a lesser extent, dehydro-aripiprazole. Aripiprazole functions as a … partial agonist at the dopamine D2 and the serotonin 5-HT1A receptors, and as an antagonist at the serotonin 5-HT2A receptor

Matched Description: chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria … . Gemifloxacin inhibits DNA gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent … supercoiling in bacterial DNA. The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV

Matched Description: Cipofloxacin is a second generation fluoroquinolone antibacterial active against gram-negative and … gram-positive bacteria. Cipofloxacin inhibits DNA gyrase (topoisomerase II) and topoisomerase IV … ) and topoisomerase IV causes supercoiling of the bacterial DNA. This prevents DNA replication.

Matched Description: Pseudouridine is phosphorylated by interacting with atp and a psuK resulting in the release of an … ADP, a hydrogen ion and a pseudouridine 5'-phosphate. The latter compound then reacts with water … through a pseudouridine 5'-phosphate glycosidase resulting in the release of a uracil and D-ribofuranose 5-phosphate

Matched Description: in the release of a hydrogen sulfide, a hydrogen ion and a a 2-aminoprop-2-enoate. The latter … spontaneously with water and a hydrogen ion resulting in the release of ammonium and pyruvate.

Matched Description: in the release of a hydrogen sulfide, a hydrogen ion and a a 2-aminoprop-2-enoate. The latter … spontaneously with water and a hydrogen ion resulting in the release of ammonium and pyruvate.

Matched Description: in the release of a hydrogen sulfide, a hydrogen ion and a a 2-aminoprop-2-enoate. The latter … spontaneously with water and a hydrogen ion resulting in the release of ammonium and pyruvate.