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Matched Description: progression and reduce the clinical symptoms of patients with relapsing multiple sclerosis (RMS). It can … and IFNAR2c). This drug activates the dimerization of these receptors. This action activates the … Jak tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the IFNAR … and IFNAR2c. This receptor complex also phosphorylates STAT3 homodimers. The IFNAR complex … -activated sequence (GAS) elements, which activates an inflammatory response and immunoregulation. When

Matched Proteins: Signal transducer and activator of transcription 3 … Signal transducer and activator of transcription 1-alpha/beta … Signal transducer and activator of transcription 2 … Signal transducer and activator of transcription 5A

Matched Description: hepatitis B and C infections. It can also treat genital warts, hairy cell leukemia, follicular lymphoma … , malignant melanoma, and AIDs-related Kaposi's sarcoma. Interferon alpha binds to type 1 interferon … receptors, called IFNAR1 and IFNAR2c, which upon dimerization activate two Jak tyrosine kinases (Jak1 … and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. This receptor complex … , which activates an inflammatory response and immunoregulation. The main pathway of IFNAR1 and IFNAR2 is

Matched Proteins: Signal transducer and activator of transcription 3 … Signal transducer and activator of transcription 1-alpha/beta … Signal transducer and activator of transcription 2 … Signal transducer and activator of transcription 5A

Matched Description: E. coli K-12 can utilize six existing hexitols as source of carbon and energy. Hexitols can enter … component, mannose permease IIC component and PTS system mannose-specific EIIAB component. Sorbitol-6

Matched Proteins: PTS system, N-acetylgalactosamine-and galactosamine-specific IIA component

Matched Description: through a NADPH dependent 2,5-diketo-D-gluconate reductase resulting in the release of a NADP and 5 … resulting in the release of a NADP and a 2-keto-L-gulonate. The 2-keto-L-gulonate interacts with a NADPH 2 … -keto-L-gulonate reductase resulting in a NADP and a L-idonate. The L-idonate interacts with a NADP L … -idonate 5-dehydrogenase resulting in the release of hydrogen ion, a NADPH and a 5-dehydro-D … in the release of a NADP and a D-gluconate. The other way to produce D-gluconate is by having 2,5

Matched Proteins: KDPG and KHG aldolase

Matched Proteins: Magnesium and cobalt efflux protein CorC

Matched Description: , an NADP and a L-glutamic gamma-semialdehyde. L-glutamic gamma-semialdehyde is dehydrated … spontaneously, resulting in a release of water,hydrogen ion and 1-Pyrroline-5-carboxylic acid. The latter … -proline. L-proline works as a repressor of the pyrroline-5-carboxylate reductase enzyme and glutamate 5 … -kinase. Three genetic loci, proA, proB and proC control the biosynthesis of L-proline in E … the antagonistic nucleophilic and aqueous environment found in the cell. Finally, NADPH-dependent

Matched Proteins: DNA replication and repair protein RecF

Matched Description: . strain ADP1 not only efficiently utilizes salicylate and its derivatives as carbon sources but also … from salicylate to catechol and subsequently to succinate underscores the intricacy and efficiency of … adapt to diverse substrates and optimize its energy yield.

Matched Proteins: Lead, cadmium, zinc and mercury transporting ATPase

Matched Description: . strain ADP1 not only efficiently utilizes salicylate and its derivatives as carbon sources but also … from salicylate to catechol and subsequently to succinate underscores the intricacy and efficiency of … adapt to diverse substrates and optimize its energy yield.

Matched Proteins: Translocation and assembly module subunit TamA

Matched Description: recruitment and initiation of transcription. The operon comprises three genes: areA, areB, and areC. The AreA … and acetic acid, thereby initiating the degradation process. Subsequently, the alcohol is converted … that responds dynamically to environmental cues, ultimately facilitating the bacterium's adaptability and metabolic versatility.

Matched Proteins: Lead, cadmium, zinc and mercury transporting ATPase

Matched Description: through a NADPH dependent 2,5-diketo-D-gluconate reductase resulting in the release of a NADP and 5 … resulting in the release of a NADP and a 2-keto-L-gulonate. The 2-keto-L-gulonate interacts with a NADPH 2 … -keto-L-gulonate reductase resulting in a NADP and a L-idonate. The L-idonate interacts with a NADP L … -idonate 5-dehydrogenase resulting in the release of hydrogen ion, a NADPH and a 5-dehydro-D … in the release of a NADP and a D-gluconate. The other way to produce D-gluconate is by having 2,5

Matched Proteins: KDPG and KHG aldolase