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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517568 results

SMP0122742

Pw124070 View Pathway
Metabolite

Sorafenib Action Pathway

Homo sapiens

  • Matched Description: (primary kidney cancer). It is an inhibitor of the RAF kinase protein and cell surface kinases PDGF-beta … receptor, VEGF 2 and 3 receptor (many sources also say VEGFR 1), c-KIT receptor, and FLT-3 receptor … angiogenesis which reduces blood flow to the tumor and also for genetic transcription for cell … proliferation and replication. Sorafenib's mechanism of action works by inhibiting the cell surface … kinases, which blocks their signalling to RAF and AKT pathways which are responsible for cell

  • Drug Action

    SMP0174888

    Pw176571 View Pathway
    Metabolite

    Mirtazapine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Mirtazapine is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms … such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and vomiting … and are administered to attenuate inflammatory process in order to treat conditions such as allergic … rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells … to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and in smooth

  • Drug Action

    SMP0174895

    Pw176581 View Pathway
    Metabolite

    Meclizine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Meclizine is an H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and … hives. It is also used with pyridoxine in the treatment of nausea and vomiting in pregnancy. H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune … response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and

  • Drug Action

    SMP0174977

    Pw176663 View Pathway
    Metabolite

    Aripiprazole lauroxil H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Aripiprazole lauroxil is an ethanolamine class H1 antihistamine used to treat insomnia and allergy … symptoms such as hay fever and hives. It is also used with pyridoxine in the treatment of nausea and … receptor and are administered to attenuate inflammatory process in order to treat conditions such … as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors … in T-cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and

  • Drug Action

    SMP0646831

    Pw687176 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Bacteroides sp. 1_1_14

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease

    SMP0646838

    Pw687183 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Bacteroides sp. 4_3_47FAA

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease

    SMP0646836

    Pw687181 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Bacteroides sp. 3_1_33FAA

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease

    SMP0646832

    Pw687177 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Bacteroides sp. 3_1_19

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease

    SMP0540404

    Pw570926 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Salmonella enterica subsp. enterica serovar Agona str. SL483

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease

    SMP0646804

    Pw687149 View Pathway
    Metabolite

    Virulence (virB operon activation)

    Actinobacillus pleuropneumoniae serovar 3 str. JL03

  • Matched Description: to virB11, and is responsible for transferring T-DNA and effector proteins from the bacterium into … peptidoglycan cell wall, facilitating insertion and assembly of T4SS. virB2 encodes the major pilin … subunit, which is processed and polymerized to form the T-pilus, which is essential for DNA transfer … to the plant cell. VirB3 encodes an inner membrane protein necessary for T-DNA secretion and it … interacts with virb4 to facilitate formation of the T-pilus. virB4 and VirB11 encode ATPases that

  • Disease