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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517568 results

SMP0126292

Pw127882 View Pathway
Metabolite

Diltiazem Calcium Channel Cardiac Muscle Relaxation Action Pathway

Homo sapiens

  • Matched Description: Diltiazem is a calcium channel blocker used to treat hypertension and to manage chronic stable … angina. It can be found under the names Cardizem, Cartia, Matzim, Taztia, Tiadylt, and Tiazac. Diltiazem … is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 … cardiac and vascular smooth muscle during depolarization. Compared to dihydropyridine drugs, such as … nifedipine, that preferentially act on vascular smooth muscle and verapamil that directly acts on

  • Drug Action

    SMP0126505

    Pw128104 View Pathway
    Metabolite

    Diltiazem Calcium Channel Vasodilation Action Pathway

    Homo sapiens

  • Matched Description: Diltiazem is a calcium channel blocker used to treat hypertension and to manage chronic stable … angina. It can be found under the names Cardizem, Cartia, Matzim, Taztia, Tiadylt, and Tiazac. Diltiazem … is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 … cardiac and vascular smooth muscle during depolarization. Compared to dihydropyridine drugs, such as … nifedipine, that preferentially act on vascular smooth muscle and verapamil that directly acts on

  • Drug Action

    SMP0120865

    Pw122126 View Pathway
    Metabolite

    Joubert Syndrome

    Rattus norvegicus

  • Matched Description: , including the lack or underdevelopment of the part of the brain that regulates balance and coordination … and an abnormal brain stem. The symptoms affect a variety of body parts in the patient, including … apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. Many … molar tooth imprint that shows up on brain scans of the patient, a visualization of the malformed brain stem and cerebellar vermis.
  • Matched Proteins: Autophagy and beclin 1 regulator 1

  • Disease

    SMP0120646

    Pw121902 View Pathway
    Metabolite

    Joubert Syndrome

    Mus musculus

  • Matched Description: , including the lack or underdevelopment of the part of the brain that regulates balance and coordination … and an abnormal brain stem. The symptoms affect a variety of body parts in the patient, including … apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability. Many … molar tooth imprint that shows up on brain scans of the patient, a visualization of the malformed brain stem and cerebellar vermis.
  • Matched Proteins: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

  • Disease

    SMP0570184

    Pw603753 View Pathway
    Metabolite

    Necroptosis

    Homo sapiens

  • Matched Description: Necroptosis is initiated by the activation of death receptors such as TNF receptors (TNFRSF1A and … TNFRSF10A) and FAS (TNFRSF6). When these receptors are activated by their ligands, they recruit FADD … and activate RIPK1. RIPK1 can then engage with RIPK3, forming the RIPK1-RIPK3 complex, which is … , membrane rupture, and release of intracellular contents. Moreover, interferons, such as interferon … inflammation and immune responses. The TRPM7 ion channel is also implicated in necroptosis by mediating
  • Matched Proteins: Signal transducer and activator of transcription 1-alpha/beta

  • Signaling

    SMP0479098

    Pw500992 View Pathway
    Metabolite

    Lipopolysaccharide Biosynthesis III

    Helicobacter cinaedi CCUG 18818 = ATCC BAA-847

  • Matched Description: start from the fructose 6-phosphate that is either produced in the glycolysis and pyruvate … resulting into a L-glutamic acid and a glucosamine 6-phosphate. The latter compound is isomerized through … and N-acetyl-glucosamine 1-phosphate. This compound interact with UTP and hydrogen ion through the … bifunctional protein glmU resulting in a pyrophosphate and a UDP-N-acetylglucosamine. This compound … resulting in a holo-[acp] and a UDP-3-O[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine. This
  • Matched Proteins: Magnesium and cobalt efflux protein

  • Metabolic

    SMP0401824

    Pw413001 View Pathway
    Metabolite

    Lipopolysaccharide Biosynthesis

    Bacteroides xylanisolvens XB1A

  • Matched Description: either the fructose 6-phosphate produced by glycolysis and pyruvate dehydrogenase or obtained from the … and a glucosamine 6-phosphate. The latter compound is isomerized through a phosphoglucosamine mutase … through a bifunctional protein glmU resulting in a Coenzyme A, hydrogen ion and N-acetyl-glucosamine 1 … -phosphate. The latter interacts with UTP and hydrogen ion through the bifunctional protein glmU … resulting in a pyrophosphate and a UDP-N-acetylglucosamine. UDP-N-acetylglucosamine iinteracts with (3R)-3
  • Matched Proteins: ABC-type multidrug transport system, ATPase and permease components

  • Metabolic

    SMP0422563

    Pw435923 View Pathway
    Metabolite

    Oxidative Phosphorylation

    Barnesiella intestinihominis YIT 11860

  • Matched Description: acid, resulting in a fumaric acid and ubiquinol. Ubiquinone interacts with succinic acid through a … cofactors, ferroheme b, 2FE-2S, FAD, and 3Fe-4S iron-sulfur cluster. Then 2 ubiquinol interact with … oxygen and 4 hydrogen ion through a cytochrome bd-I terminal oxidase resulting in a 4 hydrogen ion … transferred into the periplasmic space, 2 water returned into the cytoplasm and 2 ubiquinone, which … and 4 hydrogen ion through a cytochrome bd-II terminal oxidase resulting in a 4 hydrogen ion
  • Matched Proteins: Succinate dehydrogenase and fumarate reductase iron-sulfur protein

  • Metabolic

    SMP0405665

    Pw417274 View Pathway
    Metabolite

    Lipopolysaccharide Biosynthesis

    Prevotella bivia DSM 20514

  • Matched Description: either the fructose 6-phosphate produced by glycolysis and pyruvate dehydrogenase or obtained from the … and a glucosamine 6-phosphate. The latter compound is isomerized through a phosphoglucosamine mutase … through a bifunctional protein glmU resulting in a Coenzyme A, hydrogen ion and N-acetyl-glucosamine 1 … -phosphate. The latter interacts with UTP and hydrogen ion through the bifunctional protein glmU … resulting in a pyrophosphate and a UDP-N-acetylglucosamine. UDP-N-acetylglucosamine iinteracts with (3R)-3
  • Matched Proteins: ABC-type multidrug transport system, ATPase and permease component

  • Metabolic

    SMP0422115

    Pw435409 View Pathway
    Metabolite

    Oxidative Phosphorylation

    Bacteroides nordii CL02T12C05

  • Matched Description: acid, resulting in a fumaric acid and ubiquinol. Ubiquinone interacts with succinic acid through a … cofactors, ferroheme b, 2FE-2S, FAD, and 3Fe-4S iron-sulfur cluster. Then 2 ubiquinol interact with … oxygen and 4 hydrogen ion through a cytochrome bd-I terminal oxidase resulting in a 4 hydrogen ion … transferred into the periplasmic space, 2 water returned into the cytoplasm and 2 ubiquinone, which … and 4 hydrogen ion through a cytochrome bd-II terminal oxidase resulting in a 4 hydrogen ion
  • Matched Proteins: Succinate dehydrogenase and fumarate reductase iron-sulfur protein

  • Metabolic