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Matched Description: Ziprasidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and acute … measures symptoms of mania such as mood, insomnia, excessive energy and activity, and overall … behavior and ideation. Ziprasidone is also used as off-labeled for monotherapy in acute hypomania … , and for the treatment of delirium in the ICU. Ziprasidone presents in both oral capsule and … for dopaminergic (DA), serotonergic (5HT), adrenergic (a1), and histaminergic (HA) receptors

Matched Description: Bopindolol is a non-cardioselective beta blocker and the ester prodrug of pinolol. It can be … administered orally, where it passes through hepatic portal circulation, and enters the bloodstream and … travels to act on cardiomyocytes. In bronchial and vascular smooth muscle, bopindolol can compete with … activates SRC and nitric oxide synthase, its inhibition causes the inhibition of cAMP, PKA, SRC and nitric … Caspase 3 and Caspase 9. This Caspase cascade leads to cell apoptosis. The net result of all these

Matched Description: , hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of … histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act … blood vessels, and in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate

Matched Description: Cetirizine is a selective Histamine-1 antagonist drug used in allergic rhinitis and chronic … urticaria. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are … , allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit … the immune response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of … lungs and intestines to relax those muscles. H1-antihistamines interfere with the agonist action of

Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes … . Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R … (+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. In bronchial and vascular smooth … production, which then activates SRC and nitric oxide synthase, its inhibition causes the inhibition … of cAMP, PKA, SRC and nitric oxide synthase signaling. Following this chain of reactions, we see

Matched Description: -depressive disorder, and insomnia. H1-antihistamines interfere with the agonist action of histamine at … the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions … such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … , and in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines interfere … with the agonist action of histamine at the H1 receptor and are administered to attenuate

Matched Description: Olopatadine is a histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune … response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and … at the H1 receptor and are administered to attenuate inflammatory process in order to treat

Matched Description: Tamsulosin is an alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign … prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Tamsulosin is a … blocker of alpha-1A and alpha-1D adrenoceptors but about 70% of the alpha-1 adrenoceptors in the prostate … relaxed and urinary flow is improved. Alpha-1A adrenergic receptor are coupled to the Gq signaling … Phosphatidylinositol (3,4,5)-trisphosphate to inositol (3,4,5)-trisphosphate (IP3) and

Matched Description: ) infections in combination with other antiviral agents, Ombitasvir, Paritaprevir, and Ritonavir. Hepatitis … lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and … -dependent endocytosis. RNA is released from the mature Hepatitis C virion and translated at the rough … endoplasmic reticulum into a single Genome polyprotein. The genome polyprotein is cleaved by host and … viral proteases into 10 viral proteins. The nucleocapsid protein core and the two envelope proteins E1

Matched Description: Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to … increase alertness. The cardiovascular effects are extensive and can help with headaches, migraines … other chemicals present in it. This means that much of the research is not well understood, and … vessels in the neck and head. The adenosine A2A receptors likely have a higher affinity for caffeine … in the head and neck. The adenosine A2A receptor activates adenylate cyclase which catalyzes ATP