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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 509285 results

SMP0130951

Pw132619 View Pathway
Metabolite

Heparin

Mus musculus

  • Matched Description: Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring … anticoagulants. Specifically it is also used in the treatment of heart attacks and unstable angina. It is given … inside blood specimen test tubes and kidney dialysis machines. Heparin acts as an anticoagulant … , preventing the formation of clots and extension of existing clots within the blood. While heparin … . Heparin is usually stored within the secretory granules of mast cells and released only into the

  • Physiological

    SMP0130953

    Pw132621 View Pathway
    Metabolite

    Heparin

    Bos taurus

  • Matched Description: Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring … anticoagulants. Specifically it is also used in the treatment of heart attacks and unstable angina. It is given … inside blood specimen test tubes and kidney dialysis machines. Heparin acts as an anticoagulant … , preventing the formation of clots and extension of existing clots within the blood. While heparin … . Heparin is usually stored within the secretory granules of mast cells and released only into the

  • Physiological

    SMP0126325

    Pw127918 View Pathway
    Metabolite

    Pentazocine Opioid Antagonist Action Pathway

    Homo sapiens

  • Matched Description: receptors and as an agonist of the kappa-type opioid receptor on neurons of the central nervous system (CNS … ). The binding of pentazocine on mu-type opioid receptors and kappa-type opioid receptors can lead … to decreased levels of neuronal excitability and hyperpolarization. The preponderance of evidence … . This allows calcium to enter the neuron and depolarize. The inhibition of mu-opioid receptors … depolarize and the high concentration of calcium releases GABA into the synapse which binds to GABA

  • Drug Action

    SMP0126574

    Pw128175 View Pathway
    Metabolite

    Salbutamol Action Pathway

    Homo sapiens

  • Matched Description: , Proair, Proventil, Ventolin, and Xopenex. Salbutamol is a short-acting, selective beta2-adrenergic … receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 … - and S-isomers. The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer … and the S-isomer has been associated with toxicity. This lead to the development of levalbuterol … used for acute episodes of bronchospasm caused by bronchial asthma, chronic bronchitis and other

  • Drug Action

    SMP0012055

    Pw012917 View Pathway
    Metabolite

    cis-Zeatin-O-Glucoside Biosynthesis

    Arabidopsis thaliana

  • Matched Description: , or cytokinesis, in plant roots and shoots. They are involved primarily in cell growth and … differentiation, but also affect apical dominance, axillary bud growth, and leaf senescence. Zeatin is an … prenylation of tRNA molecules and dimethylallyl diphosphate precursors provided through the mevalonate … cytokinins. O-glucosylation is reversible and is hypothesized to be involved with transport, storage, and … protection against zeatin oxidases. Only the enzymes that catalyze the first and last steps of

  • Metabolic

    SMP0130950

    Pw132618 View Pathway
    Metabolite

    Heparin

    Homo sapiens

  • Matched Description: Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring … anticoagulants. Specifically it is also used in the treatment of heart attacks and unstable angina. It is given … inside blood specimen test tubes and kidney dialysis machines. Heparin acts as an anticoagulant … , preventing the formation of clots and extension of existing clots within the blood. While heparin … . Heparin is usually stored within the secretory granules of mast cells and released only into the

  • Physiological

    SMP0130952

    Pw132620 View Pathway
    Metabolite

    Heparin

    Rattus norvegicus

  • Matched Description: Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring … anticoagulants. Specifically it is also used in the treatment of heart attacks and unstable angina. It is given … inside blood specimen test tubes and kidney dialysis machines. Heparin acts as an anticoagulant … , preventing the formation of clots and extension of existing clots within the blood. While heparin … . Heparin is usually stored within the secretory granules of mast cells and released only into the

  • Physiological

    SMP0001892

    Pw001878 View Pathway
    Metabolite

    ara Operon

    Escherichia coli

  • Matched Description: arabinose is not present, it binds to the DNA in two specific locations, forming a loop in the DNA and … protein dimer, preventing it from forming the DNA loop and instead binding to the activator binding site … upstream of the promoter. This binding helps RNA polymerase to bind and transcribe the operon … absence of glucose, cAMP levels build up in the cell, and it can bind to and activate CRP. The … presence of both activated CRP and the arabinose operon regulatory protein promote the binding of RNA

  • Signaling

    SMP0691496

    Missing View Pathway
    Metabolite

    Oxygen - Fnr

    Bacillus subtilis

  • Matched Description: The oxygen effector pathway, regulated by the Fnr (fumarate and nitrate reduction) regulog, plays a … . Under anaerobic (low oxygen) conditions, Fnr is activated and modulates gene expression to favor … , O2, is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and … concentration directly via the disassembly and reassembly of the [4Fe-4S] clusters. Anaerobic, de novo … containing two [4Fe-4S] clusters. This, in turn, enhances the affinity of FNR for specific DNA targets and

  • Signaling

    SMP0125031

    Pw126563 View Pathway
    Metabolite

    Capecitabine Action Pathway (New)

    Homo sapiens

  • Matched Description: indicated to treat colon, colorectal and breast cancer. Capecitabine is a prodrug, that is enzymatically … converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows … cancer resistant to both paclitaxel and an anthracycline-containing chemotherapy regimen. May also be … '-deoxyuridine 5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP), within normal and tumour … cells. These metabolites cause cell injury by two different mechanisms. First, FdUMP and the folate

  • Drug Action