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Matched Description: HIV/AIDS (especially HIV-1). Nevirapine binds and inhibits reverse transcriptase to create … interruption on catalytic site of enzyme so that it can prevent the activities of RNA-dependent and DNA

Matched Description: , triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and … (PPARα) to alter lipid metabolism and treat primary hypercholesterolemia, mixed dyslipidemia, and … severe hypertriglyceridemia. Fenofibrate requires once daily dosing and has a half-life of 19-27 … UGT1A9. Reduction of the carbonyl group is primarily mediated by CBR1 and minorly by AKR1C1, AKR1C2 … , AKR1C3, and AKR1B1. 5-25% of a dose of fenofibrate is eliminated in the feces, while 60-88% is

Matched Description: Physostigmine is a cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity … cross the blood-brain barrier and is used when central nervous system effects are desired, as in … acetyl-coa and choline, and stored into synaptic vesicles. When an action potential arrives at the … . This triggers the docking of the synaptic vesicle and release of acetylcholine into the synapse … increase results in increased aqueous humor flow and a decrease in intraocular pressure. The

Matched Description: current research and biotransformer analysis. Technetium Tc-99m mebrofenin passes through the liver … and is then excreted from the body mainly through the kidney.

Matched Description: determined by current research and biotransformer analysis. Aluminum zirconium octachlorohydrex gly … passes through the liver and is then excreted from the body mainly through the kidney.

Matched Description: determined by current research and biotransformer analysis. Undecoylium chloride iodine complex passes … through the liver and is then excreted from the body mainly through the kidney.

Matched Description: the human body as determined by current research and biotransformer analysis. Sodium 1,2-Dipalmitoyl … -sn-glycero-3-phospho-(1'-rac-glycerol) passes through the liver and is then excreted from the body mainly through the kidney.

Matched Description: current research and biotransformer analysis. Indocyanine green acid form passes through the liver and

Matched Description: cAMP dependent protein kinase is a signalling molecule, found in the nucleus and cytoplasm of cells … . Cellular regulation and signal transduction in eukaryotic cells is driven by the phosphorylation

Matched Description: to IP3 and diacylglycerol to activate protein kinase C. IP3 releases calcium from the endoplasmic … reticulum. PIP3 is an important regulator of AKT signaling and downstream pathways.