SMP0059110
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Cinnarizine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0057581
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Triprolidine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0175076
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Hydroxyzine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0175146
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Chlorprothixene H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0125764
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Sucrase-Isomaltase Deficiency
Homo sapiens
Matched Description: Congenital sucrase-isomaltase deficiency is a rare inborn error of metabolism (IEM) and autosomal … . Sucrase-isomaltase catalyzes the breakdown of sucrose, maltose and larger carbohydrates. Sucrose … and maltose are disaccharides, and are broken down into simple sugars during digestion. Sucrose is … broken down into glucose and fructose, while maltose is broken down into two glucose molecules. This … disorder is characterized by stomach cramps, bloating, excess gas production, and diarrhea after
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SMP0059702
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Phenbenzamine H1-Antihistamine Action
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0059865
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Azatadine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process … in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … . Reducing the activity of the NF-κB immune response transcription factor through the phospholipase C and … the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore
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SMP0059872
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Doxepin H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in … order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … . Reducing the activity of the NF-κB immune response transcription factor through the phospholipase C and … the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore
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SMP0060058
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Bepotastine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0058923
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Cyclizine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process … in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … . Reducing the activity of the NF-κB immune response transcription factor through the phospholipase C and … the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore
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