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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 528227 results

SMP0062625

Pw063580 View Pathway
Metabolite

Propiomazine H1-Antihistamine Action

Homo sapiens

  • Matched Description: action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order … to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of … pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering

  • Drug Action

    SMP0062788

    Pw063744 View Pathway
    Metabolite

    Clocinizine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. Reducing the activity of the NF-κB immune response transcription factor through the … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen … presentation and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic … barrier and cause sedation and other adverse central nervous system (CNS) effects (e.g. nervousness and

  • Drug Action

    SMP0062795

    Pw063751 View Pathway
    Metabolite

    Homochlorcyclizine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and … the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and

  • Drug Action

    SMP0062881

    Pw063838 View Pathway
    Metabolite

    Alcaftadine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause

  • Drug Action

    SMP0062883

    Pw063840 View Pathway
    Metabolite

    Deptropine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of pro … -inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering

  • Drug Action

    SMP0058936

    Pw059870 View Pathway
    Metabolite

    Hydroxyzine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause

  • Drug Action

    SMP0058964

    Pw059899 View Pathway
    Metabolite

    Buclizine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process … in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … . Reducing the activity of the NF-κB immune response transcription factor through the phospholipase C and … the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore

  • Drug Action

    SMP0059058

    Pw059995 View Pathway
    Metabolite

    Cetirizine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause

  • Drug Action

    SMP0126580

    Pw128181 View Pathway
    Metabolite

    Thiothixene Dopamine Antagonist Action Pathway

    Homo sapiens

  • Matched Description: and D4 - different antipsychotic properties on productive and unproductive symptoms), on serotonergic … -receptors (5-HT1 and 5-HT2, with anxiolytic, antidepressive and antiaggressive properties as well as … pressure, sedation and ejaculation difficulties), on histaminergic-receptors (H1-receptors, sedation … , antiemesis, vertigo, fall in blood pressure and weight gain), alpha1/alpha2-receptors … and incontinence as well as sexual dysfunction, but may also attenuate pseudoparkinsonism

  • Drug Action

    SMP0126432

    Pw128030 View Pathway
    Metabolite

    Betrixaban Action Pathway

    Homo sapiens

  • Matched Description: Betrixaban is an anticoagulant that targets and inhibits factor Xa in order to prevent venous … thromboembolism. Due to its interaction with factor Xa, the coagulant factor is no longer free and unable … to form the prothrombinase complex. Betrixaban is administered orally and rapidly absorbed, if … eliminated via the gastrointestinal system, feces and urine. Some possible adverse effects are … bleeding, hypersensitivity and minimal hepatotoxicity. The anticoagulant does interact with food, this

  • Drug Action