SMP0646231
View Pathway
|
Pyrimidine Ribonucleosides Degradation
Helicobacter bilis ATCC 43879
Matched Description: Cytidine and uridine are transported through their corresponding nucleoside hydrogen symporters … . Once cytidine is incorporated into the cytosol, it is deaminated through a reaction with water and a … hydrogen ion through a cytidine deaminase resulting in the release of ammonium and uridine. Uridine … and an alpha-D-ribose-1-phosphate. This compound is then transformed into an isomer D-ribose 5
|
SMP0540197
View Pathway
|
Mechanisms of Fibrosis
Homo sapiens
Matched Description: (ECM) components, leading to the thickening and scarring of tissues. This process is often triggered by … , where it activates genes that promote the production of ECM proteins like collagen and fibronectin … , contributing to the progressive deposition of these components and the formation of scar tissue … . This ECM accumulation is a hallmark of fibrosis. Additionally, SMAD7 and ERK 1/2 act as negative … /β-catenin pathway, which plays a crucial role in the activation of fibroblasts and their
|
SMP0474686
View Pathway
|
Allantoin Degradation (Anaerobic)
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Matched Description: with water and 2 hydrogen ions through an allantoate amidohydrolase resulting in the release of a … carbon dioxide, ammonium and an S-ureidoglycine. The latter compund is further degrades through a S … -ureidoglycine aminohydrolase resulting in the release of an ammonium and an S-ureidoglycolate.
S … a NAD driven ureidoglycolate dehydrogenase resulting in the release of a hydrogen ion , an NADH and … NADPH, a hydroge ion and an oxalurate.
It is hypothesized that oxalurate can interact with a
|
SMP0474720
View Pathway
|
Allantoin Degradation (Anaerobic)
Escherichia coli (strain 55989 / EAEC)
Matched Description: with water and 2 hydrogen ions through an allantoate amidohydrolase resulting in the release of a … carbon dioxide, ammonium and an S-ureidoglycine. The latter compund is further degrades through a S … -ureidoglycine aminohydrolase resulting in the release of an ammonium and an S-ureidoglycolate.
S … a NAD driven ureidoglycolate dehydrogenase resulting in the release of a hydrogen ion , an NADH and … NADPH, a hydroge ion and an oxalurate.
It is hypothesized that oxalurate can interact with a
|
SMP0447790
View Pathway
|
Propanoate Metabolism
Methylobacterium mesophilicum SR1.6/6
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|
SMP0645101
View Pathway
|
Propanoate Metabolism
Bacteroides stercoris ATCC 43183
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|
SMP0645102
View Pathway
|
Propanoate Metabolism
Dysgonomonas gadei ATCC BAA-286
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|
SMP0448047
View Pathway
|
Propanoate Metabolism
Parasutterella excrementihominis YIT 11859
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|
SMP0645106
View Pathway
|
Propanoate Metabolism
Ochrobactrum intermedium LMG 3301
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|
SMP0444343
View Pathway
|
Propanoate Metabolism
Prevotella copri
Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate
|