SMP0126658
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Ergoloid mesylate Mechanism of Action Action Pathway
Homo sapiens
Matched Description: : dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the … fungus Claviceps purpurea and are all derivatives of the tetracyclic compound 6-methylergonovine … partial agonism/antagonism of adrenergic, dopaminergic and serotonergic receptors. The pharmacological
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SMP0125586
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Hyperphenylalaninemia Due to DHPR-Deficiency
Homo sapiens
Matched Description: encoding a reductase enzyme, and from there a chain reaction of effects lead to the observed … breakdown of many several amino acids, such as phenylalanine, is reduced and as a result their levels … include: dysphagia, global development delay, microcephaly, and intellectual disability (among
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SMP0349089
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Methylphosphonate Degradation I
Escherichia coli HS
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0349101
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Methylphosphonate Degradation I
Escherichia coli O26:H11 str. 11368
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0349096
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Methylphosphonate Degradation I
Escherichia coli S88
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0349390
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Methylphosphonate Degradation I
Acetomicrobium hydrogeniformans
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0565252
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Galactan utilization: ganS, ganP, ganQ, ganA, ganB
Bacillus subtilis (strain 168)
Matched Description: regulator) and glucose. The operon in activated by the presence of galactobiose which is transported … ), ganA (Beta-galactosidase) and ganB (O07013). GanS, ganP, ganQ and msmX (Oligosaccharides import ATP
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SMP0127069
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Dopamine Action Pathway
Homo sapiens
Matched Description: many heart problems and diseases. Dopamine is a precursor to norepinephrine in the sympathetic … membrane, causing the channels to open and allow Ca2+ into the cell. This causes a high concentration … + binds to troponin to cause cardiac muscle contractions and therefore, an increased heart rate. This … helps conditions like Arrhythmia, myocardial infarctions, open-heart surgery, and trauma-induced … through norepinephrine in noradrenergic neurons outside the brain, and especially in the heart. Low
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SMP0125137
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Dopamine Action Pathway
Homo sapiens
Matched Description: many heart problems and diseases. Dopamine is a precursor to norepinephrine in the sympathetic … membrane, causing the channels to open and allow Ca2+ into the cell. This causes a high concentration … + binds to troponin to cause cardiac muscle contractions and therefore, an increased heart rate.
This … helps conditions like Arrhythmia, myocardial infarctions, open-heart surgery, and trauma-induced … through norepinephrine in noradrenergic neurons outside the brain, and especially in the heart. Low
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SMP0126575
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Nylidrin Action Pathway
Homo sapiens
Matched Description: Nylidrin is a vasodilator used to treat patients with peripheral vascular disorders, and elderly … , which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies … patients with mild to moderate symptoms of cognitive, emotional and physical impairment. his drug is … processes. Signaling by various hormones and neurotransmitters, as well as photons and odors, follows … affinity for circulating epinephrine and a lower affinity to norepinephrine released by sympathetic
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