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Serine
hydroxymethyltransferase,
cytosolic
Methylenetetrahydrofolate
reductase
Methionine
synthase
Cystathionine
gamma-lyase
Cystathionine
beta-synthase
Cystathionine
beta-synthase
Betaine--
homocysteine S-
methyltransferase
1
S-
adenosylmethionine
decarboxylase
proenzyme
Spermidine
synthase
S-methyl-5'-
thioadenosine
phosphorylase
Adenosylhomocysteinase
Betaine--
homocysteine S-
methyltransferase
1
L-amino-acid
oxidase
Methionine--tRNA
ligase,
cytoplasmic
Methionyl-tRNA
formyltransferase,
mitochondrial
S-
adenosylmethionine
synthase
Choline
dehydrogenase,
mitochondrial
Methionine-R-
sulfoxide
reductase B3
Methionine-R-
sulfoxide
reductase B2,
mitochondrial
Glycine N-
methyltransferase
L-Homoserine
L-Cysteine
Homocysteine
Tetrahydrofolic
acid
L-Serine
5,10-Methylene-
THF
Glycine
5-
Methyltetrahydrofolic
acid
L-Methionine
L-Cystathionine
H
2
O
2-Ketobutyric
acid
L-Serine
H
2
O
L-Serine
H
2
O
S-
Adenosylmethionine
S-
Adenosylmethioninamine
CO
2
Putrescine
5'-
Methylthioadenosine
Spermidine
P
i
5-
Methylthioribose
1-phosphate
L-Methionine
S-
Adenosylhomocysteine
Adenosine
βine
Dimethylglycine
H
2
O
O
2
2-Oxo-4-
methylthiobutanoic
acid
NH
3
H
2
O
2
ATP
AMP
PP
i
10-
Formyltetrahydrofolate
Tetrahydrofolic
acid
ATP
P
i
PP
i
Choline
Methionine
sulfoxide
Sarcosine
Glycine
Pyridoxal
5'-phosphate
Zinc (II) ion
Pyridoxal
5'-phosphate
Pyridoxal
5'-phosphate
Zinc (II) ion
FAD
Acceptor
Reduced
acceptor
oxidized
thioredoxin
reduced
thioredoxin
tRNA(Met)
L-
Methionyl-
tRNA(Met)
N-
formylmethionyl-
tRNA(fMet)
Glycine and
Serine
Metabolism
Cysteine
Metabolism
Sulfate/Sulfite
Metabolism
FAD
Pyridoxal
5'-phosphate
Zinc (II) ion
NAD
Magnesium
Potassium
Zinc
Zinc
FAD
Intracellular space
Nuclear envelope
Mitochondria
Mitochondria