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CAD protein
CAD protein
CAD protein
Dihydroorotate
dehydrogenase
(quinone),
mitochondrial
Uridine
monophosphate
synthetase
isoform A
Uridine
monophosphate
synthetase
isoform A
Soluble
calcium-
activated
nucleotidase 1
UMP-CMP kinase
2,
mitochondrial
Nucleoside
diphosphate
kinase 6
Soluble
calcium-
activated
nucleotidase 1
GTP:AMP
phosphotransferase,
mitochondrial
Inosine
triphosphate
pyrophosphatase
CTP synthase 1
Soluble
calcium-
activated
nucleotidase 1
Nucleoside
diphosphate
kinase 6
Soluble
calcium-
activated
nucleotidase 1
UMP-CMP kinase
2,
mitochondrial
Cytosolic
purine
5'-nucleotidase
Guanine
deaminase
Cytosolic
purine
5'-nucleotidase
Uridine
phosphorylase 2
Dihydropyrimidine
dehydrogenase
[NADP(+)]
Dihydropyrimidinase
Beta-
ureidopropionase
Ribonucleoside-
diphosphate
reductase large
subunit
Nucleoside
diphosphate
kinase 6
UMP-CMP kinase
2,
mitochondrial
Cytosolic
purine
5'-nucleotidase
Uridine-
cytidine
kinase-like 1
Cytidine
deaminase
Thymidine
phosphorylase
Deoxycytidylate
deaminase
Thymidine
kinase,
cytosolic
Thymidylate
synthase
Thymidylate
synthase
Soluble
calcium-
activated
nucleotidase 1
Nucleoside
diphosphate
kinase 6
Soluble
calcium-
activated
nucleotidase 1
Cytosolic
purine
5'-nucleotidase
Thymidine
kinase,
cytosolic
Thymidine
phosphorylase
Dihydropyrimidine
dehydrogenase
[NADP(+)]
Deoxyuridine
5'-triphosphate
nucleotidohydrolase,
mitochondrial
Nucleoside
diphosphate
kinase 6
Thymidylate
synthase
Ribonucleoside-
diphosphate
reductase large
subunit
Uridine-
cytidine
kinase-like 1
Beta-
ureidopropionase
Dihydropyrimidinase
Uridine triphosphate
Cytidine triphosphate
Uridine 5'-diphosphate
CDP
dCTP
Thymidine 5'-triphosphate
β-Alanine
L-Glutamine
Carbamoyl phosphate
Phosphoribosyl pyrophosphate
3-Aminoisobutanoic acid
ATP
H
2
O
HCO
3
-
ADP
P
i
Ureidosuccinic acid
L-Dihydroorotic acid
Quinone
Orotic acid
Orotidylic acid
Uridine 5'-monophosphate
H
2
O
P
i
ATP
ADP
ADP
ATP
H
2
O
P
i
ADP
AMP
H
2
O
PP
i
ATP
ADP
P
i
dCTP
H
2
O
P
i
ADP
ATP
H
2
O
Cytidine monophosphate
P
i
ADP
ATP
H
2
O
Cytidine
P
i
H
2
O
Uridine
NH
3
H
2
O
P
i
P
i
Uracil
Ribose 1-phosphate
NADP
Accumulation
Dihydrouracil
NADPH
H
2
O
Accumulation
Ureidopropionic acid
H
2
O
NH
3
CO
2
H
2
O
dCDP
ATP
ADP
dCMP
ATP
ADP