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Pathway Description
Erythromycin Action Pathway
Homo sapiens
Category:
Metabolite Pathway
Sub-Category:
Drug Action
Created: 2013-08-22
Last Updated: 2019-08-16
Erythromycin is a bacteriostatic macrolide antibiotic antibiotic that can be used for treating various bacterial infections by inhibiting the bacterial protein synthesis. Erythromycin is produced from Streptomyces erythreus. Erythromycin can bind to 50S ribosomal subunits near the donor site reversibly. Blocking tRNA can prevent the translocation of peptides, which lead to inhibition of bacterial protein synthesis.
References
Erythromycin Pathway References
Erythromycin (CPhA monograph). (2009). e-CPS (online version of Compendium of Pharmaceuticals and Specialties). Retrieved July 17, 2009.
Song, K.S. Ribosomal protein synthesis inhibitors. In S. Offermanns, & W. Rosenthal (Eds.). Encyclopedic reference of molecular pharmacology. (2004) p. 827-833. Berlin, Germany: Springer.
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