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CREB3L2- PPARgamma Acetylglutamate kinase Acetylornithine/succinyldiaminopimelate aminotransferase Carbamoyl- phosphate synthase large chain Carbamoyl- phosphate synthase small chain Argininosuccinate synthase Argininosuccinate lyase Arginine N- succinyltransferase N- succinylarginine dihydrolase Succinylornithine transaminase N- succinylglutamate 5-semialdehyde dehydrogenase Succinylglutamate desuccinylase Gamma- glutamylputrescine synthetase Gamma- glutamylputrescine oxidoreductase Gamma- glutamyl- gamma- aminobutyraldehyde dehydrogenase Putrescine aminotransferase Gamma- aminobutyraldehyde dehydrogenase 4-aminobutyrate aminotransferase_ 4-aminobutyrate aminotransferase Aldehyde dehydrogenase- like protein yneI Acetylornithine deacetylase Biodegradative arginine decarboxylase N-acetyl- gamma- glutamyl- phosphate reductase Ornithine carbamoyltransferase chain F Ornithine carbamoyltransferase chain I Agmatinase Gamma- glutamyl- gamma- aminobutyrate hydrolase Succinate- semialdehyde dehydrogenase [NADP+] Succinic acid Succinic acid L-Glutamic acid Acetyl-CoA CoA H+ N-Acetyl-L- glutamic acid ATP ADP N-Acetyl-L- glutamyl 5-phosphate N-Acetyl-L- glutamate 5-semialdehyde L-Glutamic acid Oxoglutaric acid N- Acetylornithine HCO3- H2O L-Glutamine ATP ADP Pi L-Glutamic acid H+ Carbamoyl phosphate ATP Citrulline L-Aspartic acid PPi AMP Argininosuccinic acid Fumaric acid L-Arginine Succinyl-CoA CoA H+ N2-succinyl- L-arginine H2O H+ CO2 Ammonium N2-Succinyl- L-ornithine Oxoglutaric acid L-Glutamic acid N2-Succinyl- L-glutamic acid 5-semialdehyde H2O NAD H+ NADH N2- succinylglutamate H2O L-Glutamic acid Putrescine ATP L-Glutamic acid Pi ADP H+ γ-glutamyl-L- putrescine O2 H2O 4-(γ- glutamylamino)butanal Ammonium H2O2 H2O NADP 4- (Glutamylamino) butanoate H+ NADPH Oxoglutaric acid L-Glutamic acid 4- Aminobutyraldehyde H2O NAD H+ NADH γ-Aminobutyric acid Oxoglutaric acid Succinic acid semialdehyde L-Glutamic acid NAD H2O H+ NADH H2O Ornithine Acetic acid H+ Agmatine CO2 NADPH H+ NADP Pi Pi H+ H2O Urea H2O L-Glutamic acid H2O NADP NADPH H+ TCA Cycle TCA Cycle