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Mannose-6-
phosphate
isomerase
Mannose-6-
phosphate
isomerase
Phosphomannomutase
Mannose-1-
phosphate
guanylyltransferase
GDP-L-fucose
synthase
GDP-mannose
4,6-dehydratase
Phosphocarrier
protein HPr
Phosphocarrier
protein HPr
Mannose
permease IID
component
Mannose
permease IIC
component
PTS system
mannose-
specific EIIAB
component
β-D-
fructofuranose
6-phosphate
GDP-L-fucose
α-D-Mannose
6-phosphate
α-D-Mannose
6-phosphate
D-Mannose
1-phosphate
GTP
H
+
PP
i
Guanosine
diphosphate
mannose
GDP-4-
Dehydro-6-
deoxy-D-
mannose
NADPH
H
+
NADP
H
2
O
α-D-mannose
Glycolysis and
Pyruvate
Dehydrogenase
Colanic Acid
Building Blocks
Biosynthesis
manA
manA
manB
manC
fcl
gmd
ptsH
ptsH
manZ
manY
manX
β-D-
fructofuranose
6-phosphate
GDP-L-fucose
α-D-Mannose
6-phosphate
α-D-Mannose
6-phosphate
D-Mannose
1-phosphate
Guanosine
triphosphate
Hydrogen Ion
Pyrophosphate
Guanosine
diphosphate
mannose
GDP-4-
Dehydro-6-
deoxy-D-
mannose
NADPH
Hydrogen Ion
NADP
Water
α-D-mannose
Glycolysis and
Pyruvate
Dehydrogenase
Colanic Acid
Building Blocks
Biosynthesis
manA
manA
manB
manC
fcl
gmd
ptsH
ptsH
manZ
manY
manX
βDF6P
GDP-Fuc
αDM6P
αDM6P
M1P
GTP
H
+
PP
i
GDPMan
G4D6DMn
NADPH
H
+
NADP
H
2
O
αDM
PW000785
PW000951