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Threonine/serine
transporter
tdcC
Sodium/proline
symporter
2-methylcitrate
synthase
2-methylcitrate
dehydratase
Aconitate
hydratase 2
Methylisocitrate
lyase
Protein sbm
Methylmalonyl-
CoA
decarboxylase
Uncharacterized
protein ygfH
Acetate kinase
Propionate
kinase
Phosphate
acetyltransferase
Keto-acid
formate
acetyltransferase
Threonine
dehydratase
biosynthetic
L-Threonine
Pyruvic acid
L-Threonine
H
+
H
+
Propionic acid
Propionic acid
(2Z)-2-
aminobut-2-
enoate
2-
iminobutanoate
H
2
O
H
+
Ammonium
2-Ketobutyric
acid
ATP
CoA
Propionyl-CoA
AMP
PP
i
H
2
O
Oxalacetic acid
CoA
H
+
2-Methylcitric
acid
H
2
O
cis-2-
Methylaconitate
H
2
O
Methylisocitric
acid
Succinic acid
Succinyl-CoA
Methylmalonyl-
CoA
H
+
CO
2
Propionyl-CoA
ADP
propanoyl
phosphate
ATP
P
i
CoA
CoA
Formic acid
H
+
H
2
O
4Fe-4S
Magnesium
Adenosylcobalamin
Magnesium
Threonine
Biosynthesis
Glycolysis and
Pyruvate
Dehydrogenase
Acetyl-coenzyme
A synthetase
Propionate--CoA
ligase
Formate
acetyltransferase
1
Magnesium
tdcC
putP
prpC
prpD
acnB
prpB
sbm
scpB
ygfH
ackA
tdcD
pta
tdcE
ilvA
L-Threonine
Pyruvic acid
L-Threonine
Hydrogen Ion
Hydrogen Ion
Propionic acid
Propionic acid
(2Z)-2-
aminobut-2-
enoate
2-
iminobutanoate
Water
Hydrogen Ion
Ammonium
2-Ketobutyric
acid
Adenosine
triphosphate
Coenzyme A
Propionyl-CoA
Adenosine
monophosphate
Pyrophosphate
Water
Oxalacetic acid
Coenzyme A
Hydrogen Ion
2-Methylcitric
acid
Water
cis-2-
Methylaconitate
Water
Methylisocitric
acid
Succinic acid
Succinyl-CoA
Methylmalonyl-
CoA
Hydrogen Ion
Carbon dioxide
Propionyl-CoA
Adenosine
diphosphate
propanoyl
phosphate
Adenosine
triphosphate
Phosphate
Coenzyme A
Coenzyme A
Formic acid
Hydrogen Ion
Water
Threonine
Biosynthesis
Glycolysis and
Pyruvate
Dehydrogenase
acs
prpE
pflB
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