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Malate dehydrogenase, mitochondrial Lysine-specific demethylase 2A Hypoxia- inducible factor 1-alpha Mitochondrial pyruvate carrier 1 Mitochondrial dicarboxylate carrier Mitochondrial citrate transport protein Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Pyruvate carboxylase, mitochondrial Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Isocitrate dehydrogenase [NADP] cytoplasmic NADP+-specific isocitrate dehydrogenase Isocitrate dehydrogenase [NADP], mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Fumarate hydratase, mitochondrial Egl nine homolog 1 Egl nine homolog 2 Egl nine homolog 3 L-2- hydroxyglutarate dehydrogenase, mitochondrial Methylcytosine dioxygenase TET1 Pyruvic acid FADH2 Pyruvic acid Fumaric acid Citric acid Citric acid CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid CoA Isocitric acid NAD Oxoglutaric acid CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP CoA GTP L-Malic acid NAD NADH H+ ATP HCO3- ADP Pi cis-Aconitic acid H2O H2O Isocitric acid NADP Oxoglutaric acid NADPH NADPH 2-Hydroxyglutarate NADP NADP Oxoglutaric acid NADPH Q FAD QH2 FADH2 H2O O2 Oxoglutaric acid L-Proline CO2 Succinic acid 4-Hydroxyproline NADP NADPH Oxygen Thiamine pyrophosphate Lipoamide FAD Magnesium Thiamine pyrophosphate Lipoamide FAD Biotin Manganese Fe2+ Ascorbic acid FAD Glycolysis Mitochondrial Electron Transport Chain Cytoplasmic aconitate hydratase Succinic acid 4Fe-4S 4Fe-4S Magnesium FAD 2Fe-2S Fumaric acid 4Fe-4S Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Epigenetic Regulation Oncogene Activation, Tumour-suppressor inactivation Pseudo-Hypoxia Mutant FH Citric acid Isocitric acid Oxoglutaric acid 2-Hydroxyglutarate TCA cycle Cytoplasmic aconitate hydratase Isocitrate dehydrogenase [NADP] cytoplasmic mutIDH1 Fumaric acid prolyl hydroxylase Hypoxia inducible factor 1-alpha Methylcytosine dioxygenase TET1 Lysine-specific demethylase 2A