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Mitochondria
Sideroflexin
FSF1
D-3-
phosphoglycerate
dehydrogenase 2
D-3-
phosphoglycerate
dehydrogenase 1
Phosphoserine
aminotransferase
phosphoserine
phosphatase
Serine
hydroxymethyltransferase,
mitochondrial
Serine
hydroxymethyltransferase
Aminomethyltransferase,
mitochondrial
mitochondrial
C1-
tetrahydrofolate
synthase
mitochondrial
C1-
tetrahydrofolate
synthase
mitochondrial
C1-
tetrahydrofolate
synthase
Catabolic L-
serine/threonine
dehydratase
L-Serine
L-Serine
3-
Phosphoglyceric
acid
NAD
NADH
H
+
Phosphohydroxypyruvic
acid
L-Glutamic acid
Oxoglutaric
acid
DL-O-
Phosphoserine
H
2
O
P
i
Tetrahydrofolic
acid
H
2
O
Glycine
5,10-
Methylene-THF
Tetrahydrofolic
acid
H
2
O
Glycine
5,10-
Methylene-THF
Tetrahydrofolic
acid
Ammonium
5,10-
Methylene-THF
NADP
5,10-
Methenyltetrahydrofolic
acid
NADPH
H
2
O
10-
Formyltetrahydrofolate
H
+
ADP
P
i
ATP
Formic acid
Tetrahydrofolic
acid
H
2
O
H
+
2-aminoprop-
2-enoate
2-
iminopropanoate
H
2
O
H
+
Ammonium
Pyruvic acid
Endocytosis
Mitochondria
Mitochondria
FSF1
SER33
SER3
SER1
SER2
SHM1
SHM2
GCV1
MIS1
MIS1
MIS1
CHA1
L-Serine
L-Serine
3-
Phosphoglyceric
acid
NAD
NADH
Hydrogen Ion
Phosphohydroxypyruvic
acid
L-Glutamic acid
Oxoglutaric
acid
DL-O-
Phosphoserine
Water
Phosphate
Tetrahydrofolic
acid
Water
Glycine
5,10-
Methylene-THF
Tetrahydrofolic
acid
Water
Glycine
5,10-
Methylene-THF
Tetrahydrofolic
acid
Ammonium
5,10-
Methylene-THF
NADP
5,10-
Methenyltetrahydrofolic
acid
NADPH
Water
10-
Formyltetrahydrofolate
Hydrogen Ion
Adenosine
diphosphate
Phosphate
Adenosine
triphosphate
Formic acid
Tetrahydrofolic
acid
Water
Hydrogen Ion
2-aminoprop-
2-enoate
2-
iminopropanoate
Water
Hydrogen Ion
Ammonium
Pyruvic acid
Endocytosis