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3-ketoacyl-CoA synthase ELO1 Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase Acyl-CoA synthase 3-oxoacyl- [acyl- carrier- protein] reductase Peroxisomal hydratase- dehydrogenase- epimerase 2-enoyl thioester reductase acyl-CoA thioesterase 3-ketoacyl-CoA synthase ELO1 3-oxoacyl- [acyl- carrier- protein] reductase dihydrosphingosine C-4 hydroxylase 3- ketosphinganine reductase Ceramide synthase subunit LIP1 Serine palmitoyltransferase 1 2-enoyl thioester reductase Peroxisomal hydratase- dehydrogenase- epimerase Palmityl-CoA Malonyl-CoA H+ CO2 3- Oxooctadecanoyl- CoA CoA Palmitic acid ATP CoA AMP PPi H+ NADPH NADP (3R)-3- hydroxy- stearoyl-CoA (2E)- Octadecenoyl- CoA H2O H+ NADPH Stearoyl-CoA NADP H2O H+ CoA Stearic acid H+ Malonyl-CoA 3- oxoicosanoyl- CoA CoA CO2 NADPH H+ (3R)-3- hydroxy- arachidoyl- CoA NADP H+ O2 Sphinganine H2O Phytosphingosine H+ NADPH 3- Dehydrosphinganine NADP Eicosanoyl-CoA H+ CoA N- icosanoylphytosphingosine Palmityl-CoA L-Serine H+ CoA CO2 (2E)- eicosenoyl- CoA H+ NADPH NADP H2O ferrocytochrome b5 ferricytochrome b5
Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown LIP1 LCB1 Unknown Unknown Palmityl-CoA Malonyl-CoA Hydrogen Ion Carbon dioxide 3- Oxooctadecanoyl- CoA Coenzyme A Palmitic acid Adenosine triphosphate Coenzyme A Adenosine monophosphate Pyrophosphate Hydrogen Ion NADPH NADP (3R)-3- hydroxy- stearoyl-CoA (2E)- Octadecenoyl- CoA Water Hydrogen Ion NADPH Stearoyl-CoA NADP Water Hydrogen Ion Coenzyme A Stearic acid Hydrogen Ion Malonyl-CoA 3- oxoicosanoyl- CoA Coenzyme A Carbon dioxide NADPH Hydrogen Ion (3R)-3- hydroxy- arachidoyl- CoA NADP Hydrogen Ion Oxygen Sphinganine Water Phytosphingosine Hydrogen Ion NADPH 3- Dehydrosphinganine NADP Eicosanoyl-CoA Hydrogen Ion Coenzyme A N- icosanoylphytosphingosine Palmityl-CoA L-Serine Hydrogen Ion Coenzyme A Carbon dioxide (2E)- eicosenoyl- CoA Hydrogen Ion NADPH NADP Water ferrocytochrome b5 ferricytochrome b5