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Malate dehydrogenase, mitochondrial Methylcytosine dioxygenase TET1 Lysine-specific demethylase 2A Mitochondrial pyruvate carrier 1 Mitochondrial citrate transport protein Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Succinate dehydrogenase Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Glutamate dehydrogenase 1, mitochondrial Glutaminase liver isoform, mitochondrial Isocitrate dehydrogenase [NADP] cytoplasmic NADP+-specific isocitrate dehydrogenase L-2- hydroxyglutarate dehydrogenase, mitochondrial L-2- hydroxyglutarate dehydrogenase, mitochondrial mutant Isocitrate dehydrogenase 2 [NADP], mitochondrial Isocitrate dehydrogenase [NADP] cytoplasmic Pyruvic acid FADH2 Pyruvic acid Citric acid Citric acid CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid CoA Isocitric acid NAD Oxoglutaric acid CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP Succinic acid CoA GTP L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi Q FAD QH2 cis-Aconitic acid H2O H2O NADPH Ammonium H+ L-Glutamic acid H2O NADP L-Glutamine H2O NH3 Isocitric acid NADP Oxoglutaric acid NADPH NADPH NADP NADH Oxoglutaric acid NAD NADP 2-Hydroxyglutarate NADPH NADPH NADP NAD H+ NADH H+ CO2 Thiamine pyrophosphate Lipoamide FAD Thiamine pyrophosphate Lipoamide FAD Biotin Manganese Magnesium FAD Glycolysis Mitochondrial Electron Transport Chain Magnesium 4Fe-4S 4Fe-4S Cytoplasmic aconitate hydratase L-2-Hydroxyglutaric acid 4Fe-4S Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Epigenetic Regulation Oncogene Activation, Tumour-suppressor inactivation TCA cycle Citric acid Isocitric acid Oxoglutaric acid L-2-Hydroxyglutaric acid 2-Hydroxyglutarate Oxoglutaric acid Cytoplasmic aconitate hydratase Isocitrate dehydrogenase [NADP] cytoplasmic mutIDH2 L-2-hydroxyglutarate dehydrogenase, mitochondrial L-2-hydroxyglutarate dehydrogenase, mitochondrial Lysine-specific demethylase 2A Methylcytosine dioxygenase TET1