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Protein URA2 Protein URA2 Protein URA2 aspartate transcarbamylase Dihydroorotase orotidine-5'- phosphate decarboxylase UMP kinase nucleoside diphosphate kinase CTP synthase ribonucleoside diphosphate reductase 1 Ribonucleoside- diphosphate reductase large chain 1 ribonucleoside diphosphate reductase 1 ribonucleoside diphosphate reductase 1 nucleoside diphosphate kinase deoxyuridine triphosphatase nucleoside triphosphate pyrophosphohydrolase pyrimidine deoxynucleoside triphosphate pyrophosphohydrolase nucleoside diphosphate kinase ribonucleoside- triphosphate reductase dihydroorotate dehydrogenase, type 2 Thymidylate synthase Orotate phosphoribosyltransferase 2 ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 nucleoside diphosphate kinase ribonucleoside- triphosphate reductase dCTP deaminase Ribonucleoside- diphosphate reductase large chain 1 Ribonucleoside- diphosphate reductase small chain 2 Thymidylate kinase L-Glutamine Phosphoribosyl pyrophosphate HCO3- H2O ATP ADP Pi L-Glutamic acid H+ Carbamoyl phosphate L-Aspartic acid Pi H+ N-carbamoyl- L-aspartate H+ H2O 4,5- Dihydroorotic acid Orotidylic acid H+ CO2 Uridine 5'- monophosphate ATP ADP Uridine 5'-diphosphate ATP Uridine triphosphate ADP L-Glutamine H2O ATP ADP H+ Pi L-Glutamic acid Cytidine triphosphate H2O Pi H+ CDP H2O dCDP H2O dUDP ATP ADP Deoxyuridine triphosphate H2O Pi H+ dUMP ATP dTDP ADP Thymidine 5'-triphosphate H2O dCTP Ubiquinone-1 Ubiquinol-1 Orotic acid 5,10- methenyltetrahydrofolate mono-L- glutamate Dihydrofolic acid 5-Thymidylic acid PPi H2O ATP ADP H2O H2O H+ Ammonium H2O ATP ADP Adenosine triphosphate Zinc Magnesium Magnesium Adenosine triphosphate Fe2+ Magnesium Magnesium Zinc Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Flavin Mononucleotide Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Fe3+ reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein L-Glutamate Metabolism PRPP Biosynthesis a reduced NrdH glutaredoxin- like protein Guanosine triphosphate Magnesium