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4-
hydroxybenzoate
polyprenyltransferase,
mitochondrial
Hexaprenyldihydroxybenzoate
methyltransferase,
mitochondrial
Ubiquinone
biosynthesis
monooxygenase
COQ6
2-methoxy-6-
polyprenyl-
1,4-
benzoquinol
methylase,
mitochondrial
Ubiquinone
biosynthesis
protein COQ7
homolog
Hexaprenyldihydroxybenzoate
methyltransferase,
mitochondrial
4-
Hydroxybenzoic
acid
All-trans-
hexaprenyl
diphosphate
3-Hexaprenyl-
4-
hydroxybenzoic
acid
PP
i
3-Hexaprenyl-
4,5-
Dihydroxybenzoic
acid
S-
Adenosylmethionine
S-
Adenosylhomocysteine
3-Hexaprenyl-
4-hydroxy-5-
methoxybenzoic
acid
2-Hexaprenyl-
6-
methoxyphenol
O
2
2-Hexaprenyl-
6-methoxy- 1,4-
benzoquinone
H
2
O
S-
Adenosylmethionine
2-Hexaprenyl-
3-methyl-6-
methoxy-1,4
benzoquinone
S-
Adenosylhomocysteine
O
2
NADPH
H
+
2-Hexaprenyl-
3-methyl-5-
hydroxy-6-
methoxy-1,4-
benzoquinone
NADP
H
2
O
S-
Adenosylmethionine
Ubiquinone-6
S-
Adenosylhomocysteine
Fe3+
Mitochondria
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
4-
Hydroxybenzoic
acid
All-trans-
hexaprenyl
diphosphate
3-Hexaprenyl-
4-
hydroxybenzoic
acid
Pyrophosphate
3-Hexaprenyl-
4,5-
Dihydroxybenzoic
acid
S-
Adenosylmethionine
S-
Adenosylhomocysteine
3-Hexaprenyl-
4-hydroxy-5-
methoxybenzoic
acid
2-Hexaprenyl-
6-
methoxyphenol
Oxygen
2-Hexaprenyl-
6-methoxy- 1,4-
benzoquinone
Water
S-
Adenosylmethionine
2-Hexaprenyl-
3-methyl-6-
methoxy-1,4
benzoquinone
S-
Adenosylhomocysteine
Oxygen
NADPH
Hydrogen Ion
2-Hexaprenyl-
3-methyl-5-
hydroxy-6-
methoxy-1,4-
benzoquinone
NADP
Water
S-
Adenosylmethionine
Ubiquinone-6
S-
Adenosylhomocysteine
4-HBA
ATHD
3H4H
PP
i
Dhhpba
SAMe
SAH
3-MHHB
2h6m
O
2
2H6M14B
H
2
O
SAMe
hmm14b
SAH
O
2
NADPH
H
+
hmhm14B
NADP
H
2
O
SAMe
Ubiq6
SAH
Fe3+