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dGTP phosphoribosylglycinamide formyltransferase 2 phosphoribosylformylglycinamide synthetase phosphoribosylformylglycinamide cyclo-ligase N5- carboxyaminoimidazole ribonucleotide synthetase N5- carboxyaminoimidazole ribonucleotide mutase phosphoribosylaminoimidazole- succinocarboxamide synthase adenylosuccinate lyase Putative inosine-5'- monophosphate dehydrogenase 1 adenylosuccinate synthase adenylosuccinate lyase GMP synthetase Guanylate kinase nucleoside diphosphate kinase ribonucleoside- triphosphate reductase ribonucleoside diphosphate reductase 1 ribonucleoside- triphosphate reductase ribonucleoside diphosphate reductase 1 ribonucleoside diphosphate reductase 1 AICAR transformylase / IMP cyclohydrolase cobinamide adenosyltransferase / cobalamin adenosyltransferase Succinyl-CoA ligase Succinyl-CoA ligase AICAR transformylase / IMP cyclohydrolase Adenylate kinase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase / thiamin triphosphate synthase ATP synthase subunit beta, mitochondrial nucleoside diphosphate kinase ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 nucleoside diphosphate kinase phosphoribosylamine- glycine ligase amidophosphoribosyl transferase Phosphoribosyl pyrophosphate Guanosine triphosphate N1-(5- phospho-β-D- ribosyl)glycinamide ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP Pi H+ H2O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5- Aminoimidazole ribonucleotide Pi ADP H+ HCO3- ATP N5- Carboxyaminoimidazole ribonucleotide ADP Pi H+ 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR Pi ADP H+ AICAR Fumaric acid Inosinic acid NAD H2O NADH H+ Xanthylic acid L-Aspartic acid GTP GDP Pi H+ N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP L-Glutamine H2O AMP PPi L-Glutamic acid H+ Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP H2O H2O dGDP Adenosine triphosphate H2O dATP Adenosine diphosphate H2O dADP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid CoA ADP Pi Itaconyl-CoA H2O ATP Pi H+ H2O H+ ATP ADP H2O H2O ATP ADP 5- Phosphoribosylamine Glycine ATP Pi ADP H+ H2O L-Glutamine L-Glutamic acid PPi Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium Magnesium ATP synthase / thiamin triphosphate synthase a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein PRPP Biosynthesis Folate Biosynthesis