PathBank

Pathway Description

Taurine and Hypotaurine Biosynthesis

Saccharomyces cerevisiae

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2016-02-22

Last Updated: 2026-05-29

The biosynthesis of taurine and hypotaurine is processed by the same protein, glutamate decarboxylase. Hypotaurine is produced by 3-sulfino-L-alanine reacting with glutamate decarboxylase resulting in the release of carbon dioxide and hypotaurine. Taurine is produced by L-cysteate reacting with a glutamate decarboxylase resulting in the release of Taurine and carbon dioxide

References

Taurine and Hypotaurine Biosynthesis References

Kanehisa M, Sato Y, Kawashima M, Furumichi M, Tanabe M: KEGG as a reference resource for gene and protein annotation. Nucleic Acids Res. 2016 Jan 4;44(D1):D457-62. doi: 10.1093/nar/gkv1070. Epub 2015 Oct 17.

Pubmed: 26476454

Kanehisa M, Goto S: KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000 Jan 1;28(1):27-30.

Pubmed: 10592173

Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B: The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Nature. 1997 May 29;387(6632 Suppl):90-3.

Pubmed: 9169872

Engel SR, Dietrich FS, Fisk DG, Binkley G, Balakrishnan R, Costanzo MC, Dwight SS, Hitz BC, Karra K, Nash RS, Weng S, Wong ED, Lloyd P, Skrzypek MS, Miyasato SR, Simison M, Cherry JM: The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda). 2014 Mar 20;4(3):389-98. doi: 10.1534/g3.113.008995.

Pubmed: 24374639

Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS: Global analysis of protein expression in yeast. Nature. 2003 Oct 16;425(6959):737-41. doi: 10.1038/nature02046.

Pubmed: 14562106

Highlighted elements will appear in red.

Highlight Compounds

	3-Sulfinoalanine
	Carbon dioxide
	Cysteic acid
	Hypotaurine
	Taurine

Highlight Proteins

Glutamate decarboxylase

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