Toggle navigation
PathBank
Browse
Pathways
Table of Primary Pathways
Compounds
Proteins
Search
Advanced Text Search
ChemQuery Structure Search
Molecular Weight Search
Sequence Search
Analyze
Over-Representation Analysis
Path-MAP Analysis
Pathway Enrichment Analysis
About
About PathBank
Statistics
Style Guide
Other Databases
Pathway Legend
Pathway Category Definitions
PathWhiz
Downloads
Contact Us
Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
Loading Pathway...
Error: Pathway image not found.
Endoplasmic Reticulum
3-ketoacyl-CoA
thiolase,
peroxisomal
3-hydroxy-3-
methylglutaryl-
coenzyme A
reductase 2
3-hydroxy-3-
methylglutaryl-
coenzyme A
reductase 1
Lanosterol
14-alpha
demethylase
Delta(14)-
sterol
reductase
Hydroxymethylglutaryl-
CoA synthase
mevalonate
kinase
Phosphomevalonate
kinase
Diphosphomevalonate
decarboxylase
Isopentenyl-
diphosphate
Delta-isomerase
Farnesyl
pyrophosphate
synthase
Farnesyl
pyrophosphate
synthase
Squalene
synthase
squalene
monooxygenase
Lanosterol
synthase
Lanosterol
14-alpha
demethylase
Delta(14)-
sterol
reductase
Methylsterol
monooxygenase
Methylsterol
monooxygenase
Methylsterol
monooxygenase
C-3 sterol
dehydrogenase
3-keto sterol
reductase
Methylsterol
monooxygenase
Methylsterol
monooxygenase
Methylsterol
monooxygenase
C-3 sterol
dehydrogenase
3-keto sterol
reductase
Sterol 24-C-
methyltransferase
C-8 sterol
isomerase
C-5 sterol
desaturase
C-8 sterol
isomerase
C-5 sterol
desaturase
Acetyl-CoA
CoA
Acetoacetyl-CoA
3-Hydroxy-3-
methylglutaryl-
CoA
NADPH
Mevalonic acid
NADP
CoA
5,7,24(28)-
Ergostatrienol
H
+
NADPH
O
2
ergosta-
5,7,22,24(28)-
tetraen-3-β- ol
NADP
H
2
O
H
+
NADPH
Ergosterol
NADP
Acetyl-CoA
H
2
O
3-Hydroxy-3-
methylglutaryl-
CoA
CoA
ATP
Mevalonic
acid-5P
ADP
ATP
ADP
(R)-5-
Diphosphomevalonic
acid
ATP
ADP
P
i
Isopentenyl
pyrophosphate
CO
2
Isopentenyl
pyrophosphate
Dimethylallylpyrophosphate
Isopentenyl
pyrophosphate
Geranyl-PP
PP
i
Isopentenyl
pyrophosphate
Farnesyl
pyrophosphate
PP
i
NADPH
Squalene
NADP
PP
i
Squalene
O
2
NADPH
(S)-2,3-
Epoxysqualene
H
2
O
NADP
Lanosterol
Lanosterol
O
2
NADPH
4,4-
Dimethylcholesta-
8,14,24-
trienol
Formic acid
NADP
H
2
O
NADPH
4,4-Dimethyl-
5a-cholesta-
8,24-dien-3-
b-ol
NADP
4,4-Dimethyl-
5a-cholesta-
8,24-dien-3-
b-ol
H
+
O
2
NADPH
4α-
hydroxymethyl-
4β-methyl-5α-
cholesta-
8,24-dien-3β-
ol
NADP
H
2
O
H
+
O
2
NADPH
4α-formyl-4β-
methyl-5α-
cholesta-
8,24-dien-3β-
ol
H
2
O
NADP
O
2
NADPH
4β-methyl-4α-
carboxy-
cholesta-
8,24-dien-3β-
ol
H
2
O
NADP
NADP
3-Keto-4-
methylzymosterol
CO
2
NADPH
NADPH
4a-
Methylzymosterol
NADP
4a-
Methylzymosterol
H
+
O
2
NADPH
H
2
O
NADP
4α-
hydroxymethyl-
5α-cholesta-
8,24-dien-3β-
ol
H
+
O
2
NADPH
4α-formyl-5α-
cholesta-
8,24-dien-3β-
ol
H
2
O
NADP
O
2
NADPH
4α-carboxy-
5α-cholesta-
8,24-dien-3β-
ol
H
2
O
NADP
NADP
5α-cholesta-
8,24-dien-3-
one
CO
2
NADPH
NADPH
H
+
Zymosterol
NADP
S-
Adenosylmethionine
fecosterol
S-
Adenosylhomocysteine
H
+
Episterol
H
+
O
2
ferrocytochrome
c
5,7,24(28)-
Ergostatrienol
H
2
O
ferricytochrome
c
Zymosterol
5a-cholesta-
7,24-dien-3B-
ol
7-
Dehydrodesmosterol
Desmosterol
Cholesterol
Lauroyl-CoA
CoA
CE(12:0)