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Flavonol
synthase
Flavonol
synthase
Quercetin 3-
sulfotransferase
Quercetin 3'-O-
methyltransferase
Flavonoid
3'-hydroxylase
Flavonoid
3'-hydroxylase
Flavonoid
3'-hydroxylase
Flavonol-3-O-
rhamnosyltransferase
Flavonol-3-O-
rhamnosyltransferase
Flavonol 3-O-
glucosyltransferase
Flavonol-3-O-
rhamnosyltransferase
Flavonol-3-O-
rhamnosyltransferase
Flavonol 3-O-
glucosyltransferase
Apigenin
Aromadendrin
Quercetin
Quercetin
Kaempferol
Kaempferol
Taxifolin
Oxoglutaric
acid
O
2
Succinic acid
CO
2
H
2
O
Oxoglutaric
acid
O
2
Succinic acid
CO
2
H
2
O
Phosphoadenosine
phosphosulfate
Quercetin
3'-sulfate
Adenosine
3',5'-
diphosphate
H
+
S-
Adenosylmethionine
Isorhamnetin
S-
Adenosylhomocysteine
H
+
O
2
Luteolin
H
2
O
O
2
H
2
O
O
2
H
2
O
UDP-L-rhamnose
Quercitrin
Uridine
5'-diphosphate
Uridine
diphosphate
glucose
Quercetin
3-O-rhamnoside
7-O-glucoside
Uridine
5'-diphosphate
Uridine
diphosphate
glucose
Uridine
5'-diphosphate
Isoquercitrin
UDP-L-rhamnose
Afzelin
Uridine
5'-diphosphate
Uridine
diphosphate
glucose
Kaempferol 3-O-
rhamnoside-7-
O-glucoside
Uridine
5'-diphosphate
Uridine
diphosphate
glucose
Astragalin
Uridine
5'-diphosphate
Ascorbic acid
Fe2+
Ascorbic acid
Fe2+
[Reduced
NADPH---
hemoprotein
reductase]
[Oxidized
NADPH---
hemoprotein
reductase]
[Reduced
NADPH---
hemoprotein
reductase]
[Oxidized
NADPH---
hemoprotein
reductase]
[Reduced
NADPH---
hemoprotein
reductase]
[Oxidized
NADPH---
hemoprotein
reductase]
Flavonoid
Biosynthesis
Cytoplasm
Dark green proteins are
endoplasmic
reticulum-associated
Chloroplast
Chloroplast
FLS
FLS
AtST3a
OMT1
F3'H
F3'H
F3'H
UGT78D1
UGT78D1
UGT78D2
UGT78D1
UGT78D1
UGT78D2
Apigenin
Aromadendrin
Quercetin
Quercetin
Kaempferol