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folylpolyglutamate synthetase 10- formyltetrahydrofolate synthetase serine hydroxymethyltransferase folylpolyglutamate synthetase folylpolyglutamate synthetase L-Glutamic acid ATP ADP H+ Formic acid ATP Pi ADP L-Serine H2O Glycine L-Glutamic acid ATP ADP H+ L-Glutamic acid ATP H+ ADP a tetrahydrofolate a tetrahydrofolate an N10-formyl- tetrahydrofolate 5,10- methylene- tetrahydrofolate an N10-formyl- tetrahydrofolate 5,10- methylene- tetrahydrofolate Folate Biosynthesis Cytosol
DHFS/FPGS4 THFS SHM1 DHFS/FPGS4 DHFS/FPGS4 L-Glutamic acid Adenosine triphosphate Adenosine diphosphate Hydrogen Ion Formic acid Adenosine triphosphate Phosphate Adenosine diphosphate L-Serine Water Glycine L-Glutamic acid Adenosine triphosphate Adenosine diphosphate Hydrogen Ion L-Glutamic acid Adenosine triphosphate Hydrogen Ion Adenosine diphosphate a tetrahydrofolate a tetrahydrofolate an N10-formyl- tetrahydrofolate 5,10- methylene- tetrahydrofolate an N10-formyl- tetrahydrofolate 5,10- methylene- tetrahydrofolate Folate Biosynthesis
DHFS/FPGS4 THFS SHM1 DHFS/FPGS4 DHFS/FPGS4 Glu ATP ADP H+ Formate ATP Pi ADP Ser H2O Gly Glu ATP ADP H+ Glu ATP H+ ADP AT AT AFT 5MT AFT 5MT PW012874 Cytosol
DHFS/FPGS4 THFS SHM1 DHFS/FPGS4 DHFS/FPGS4 Glu ATP ADP H+ Formate ATP Pi ADP Ser H2O Gly Glu ATP ADP H+ Glu ATP H+ ADP AT AT AFT 5MT AFT 5MT PW012874