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Aspartate-
semialdehyde
dehydrogenase
4-hydroxy-
tetrahydrodipicolinate
synthase 1,
chloroplastic
4-hydroxy-
tetrahydrodipicolinate
synthase 2,
chloroplastic
4-hydroxy-
tetrahydrodipicolinate
reductase 2,
chloroplastic
4-hydroxy-
tetrahydrodipicolinate
reductase 1,
chloroplastic
4-hydroxy-
tetrahydrodipicolinate
reductase 2,
chloroplastic
4-hydroxy-
tetrahydrodipicolinate
reductase 1,
chloroplastic
Aspartokinase
1,
chloroplastic
ATP sulfurylase
1,
chloroplastic
L-Aspartic acid
Tetrahydrodipicolinate
L-Aspartate-
semialdehyde
P
i
NADP
L-Aspartyl-4-
phosphate
NADPH
H
+
Pyruvic acid
(2S,4S)-4-
hydroxy-
2,3,4,5-
tetrahydrodipicolinic
acid
H
2
O
NADH
H
+
NAD
H
2
O
NADPH
H
+
NADP
H
2
O
ATP
ADP
Sulfate
ATP
Adenosine
phosphosulfate
PP
i
Alanine,
aspartate and
glutamate
biosynthesis
Lysine
biosynthesis
Chloroplast
Chloroplast
ASDH
DHDPS1
DHDPS2
DAPB2
DAPB1
DAPB2
DAPB1
AK1
APS1
L-Aspartic acid
Tetrahydrodipicolinate
L-Aspartate-
semialdehyde
Phosphate
NADP
L-Aspartyl-4-
phosphate
NADPH
Hydrogen Ion
Pyruvic acid
(2S,4S)-4-
hydroxy-
2,3,4,5-
tetrahydrodipicolinic
acid
Water
NADH
Hydrogen Ion
NAD
Water
NADPH
Hydrogen Ion
NADP
Water
Adenosine
triphosphate
Adenosine
diphosphate
Sulfate
Adenosine
triphosphate
Adenosine
phosphosulfate
Pyrophosphate
Alanine,
aspartate and
glutamate
biosynthesis
Lysine
biosynthesis