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Thyroglobulin Sodium/iodide cotransporter Unknown Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroglobulin Thyroid peroxidase Thyroglobulin Thyroid peroxidase Thyroid peroxidase Thyroid peroxidase Na+ Na+ Iodide Iodide Iodide Thyroxine Thyroxine Thyroxine Thyroxine Liothyronine Liothyronine Liothyronine Liothyronine Iodide H2O2 H2O H2O2 H2O Iodide H2O2 H2O H2O2 H2O L-Tyrosine Liothyronine Liothyronine Thyroxine Thyroxine L-Tyrosine L-Tyrosine L-Tyrosine L-Tyrosine L-Tyrosine Iodotyrosine 3,5-Diiodo-L- tyrosine Calcium FAD Heme 2-Aminoacrylic acid Calcium FAD Heme Calcium FAD Heme Calcium FAD Heme Thyroglobulin secretion Endocytosis Exocytosis Proteolysis Proteolysis Endocytosis Exocytosis Blood Blood Vessel Intracellular Space Thyroid follicular cell Endothelium Follicle Colloid
Tg Slc5a5 Unknown Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Sodium Sodium Iodide Iodide Iodide Thyroxine Thyroxine Thyroxine Thyroxine Liothyronine Liothyronine Liothyronine Liothyronine Iodide Hydrogen peroxide Water Hydrogen peroxide Water Iodide Hydrogen peroxide Water Hydrogen peroxide Water Thyroglobulin secretion
Tg Slc5a5 Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Na+ Na+ Iodide Iodide Iodide T4 T4 T4 T4 T3 T3 T3 T3 Iodide H2O2 H2O H2O2 H2O Iodide H2O2 H2O H2O2 H2O Tyr T3 T3 T4 T4 Tyr Tyr Tyr Tyr Tyr IYR 35DLTyr Ca2+ FAD Heme 2Amnaa Ca2+ FAD Heme Ca2+ FAD Heme Ca2+ FAD Heme Thy sec Endocytosis Exocytosis Proteolysis Proteolysis Endocytosis Exocytosis Blood Blood Vessel Intracellular Space Thyroid follicular cell Endothelium Follicle Colloid
Tg Slc5a5 Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tg Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Tpo Cybb Nox3 Cyba Nox3 Nox1 Nox4 Na+ Na+ Iodide Iodide Iodide T4 T4 T4 T4 T3 T3 T3 T3 Iodide H2O2 H2O H2O2 H2O Iodide H2O2 H2O H2O2 H2O Thy sec