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Selenocysteine
lyase
Selenide, water
dikinase 1
Cystathionine
gamma-lyase
Cystathionine
beta-synthase
Adenosylhomocysteinase
Methyltransferase-
like protein 2
S-
adenosylmethionine
synthase
isoform type-1
Methionine
adenosyltransferase
2 subunit beta
Methionine--
tRNA ligase,
cytoplasmic
3'-
phosphoadenosine
5'-
phosphosulfate
synthase 1
3'-
phosphoadenosine
5'-
phosphosulfate
synthase 1
Glutathione
hydrolase 7
Se-Methylselenocysteine
Selenite
Selenocysteine
L-Alanine
Hydrogen
selenide
ATP
H
2
O
AMP
Phosphoroselenoic
acid
P
i
Selenocystathionine
H
2
O
NH
3
2-Ketobutyric
acid
L-Serine
Selenohomocysteine
H
2
O
Se-Adenosylselenohomocysteine
H
2
O
Adenosine
Se-Adenosylselenomethionine
Selenomethionine
ATP
H
2
O
Phosphoric acid
PP
i
ATP
AMP
PP
i
ATP
Selenic acid
Adenylylselenate
PP
i
ATP
3-Phosphoadenylylselenate
ADP
γ-Glutamyl-Se-
methylselenocysteine
Selenocystine
Pyridoxal
5'-phosphate
Pyridoxal
5'-phosphate
Pyridoxal
5'-phosphate
NAD
tRNA(Met)
Selenomethionyl-
tRNA(Met)
Intestinal
Digestion and
Absorption
Aspartate
Metabolism
Glutamate
Metabolism
Alanine
Metabolism
D-Arginine and
D-Ornithine
Metabolism
Extracellular Space
Intracellular Space
Extracellular Space
SCLY
SEPHS1
CTH
CBS
AHCY
METTL2
MAT1A
MAT2B
MARS
PAPSS1
PAPSS1
GGT7
Se-
Methylselenocysteine
Selenite
Selenocysteine
L-Alanine
Hydrogen
selenide
Adenosine
triphosphate
Water
Adenosine
monophosphate
Phosphoroselenoic
acid
Phosphoric acid
Selenocystathionine
Water
Ammonia
2-Ketobutyric
acid
L-Serine
Selenohomocysteine
Water
Se-
Adenosylselenohomocysteine
Water
Adenosine
Se-
Adenosylselenomethionine
Selenomethionine
Adenosine
triphosphate
Water
Phosphoric acid
Pyrophosphate
Adenosine
triphosphate
Adenosine
monophosphate
Pyrophosphate
Adenosine
triphosphate
Selenic acid
Adenylylselenate
Pyrophosphate
Adenosine
triphosphate
3-
Phosphoadenylylselenate
Adenosine
diphosphate
γ-Glutamyl- Se-
methylselenocysteine
Selenocystine
tRNA(Met)
Selenomethionyl-
tRNA(Met)
Intestinal
Digestion and
Absorption
Aspartate
Metabolism
Glutamate
Metabolism
Alanine
Metabolism
D-Arginine and
D-Ornithine
Metabolism