Quantitative metabolomics services for biomarker discovery and validation.
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Cytochrome P450 2U1 Cytochrome P450 2U1 Cytochrome P450 2E1 Unknown Cytochrome P450 2U1 Cytochrome P450 3A28 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2U1 Cytochrome P450 2U1 Xanthine dehydrogenase/oxidase Xanthine dehydrogenase/oxidase Cytochrome P450 2U1 Cytochrome P450 3A28 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2U1 Cytochrome P450 2E1 Xanthine dehydrogenase/oxidase 5-Acetylamino-6-formylamino- 3-methyluracil 5-Acetylamino-6-amino-3- methyluracil Caffeine NADH O2 Paraxanthine NAD H2O Formaldehyde NADH O2 Theobromine NAD H2O Formaldehyde Acetyl-CoA CoA NADH O2 Theophylline NAD H2O Formaldehyde NADH O2 7-Methylxanthine NAD H2O Formaldehyde NADH O2 1-Methylxanthine NAD H2O Formaldehyde H2O O2 1-Methyluric acid H2O2 O2 H2O 7-Methyluric acid H2O2 O2 H2O 1,3,7-Trimethyluric acid H2O2 O2 H2O 1,7-Dimethyluric acid H2O2 H2O O2 3,7-Dimethyluric acid H2O2 Heme Heme Heme Heme Heme Heme Heme Heme Heme Heme FAD 2Fe-2S Molybdopterin FAD 2Fe-2S Molybdopterin Heme Heme Heme Heme Heme Heme Heme FAD 2Fe-2S Molybdopterin Endoplasmic Reticulum ER Membrane ER Lumen Lysosome Lysosomal Lumen Lysosomal Membrane Liver
Endoplasmic Reticulum Lysosome CYP2U1 CYP2U1 CYP2E1 Unknown CYP2U1 CYP3A28 CYP2E1 CYP2E1 CYP2E1 CYP2U1 CYP2U1 XDH XDH CYP2U1 CYP3A28 CYP2E1 CYP2E1 CYP2E1 CYP2U1 CYP2E1 XDH 5- Acetylamino- 6- formylamino- 3- methyluracil 5- Acetylamino- 6-amino-3- methyluracil Caffeine NADH Oxygen Paraxanthine NAD Water Formaldehyde NADH Oxygen Theobromine NAD Water Formaldehyde Acetyl-CoA Coenzyme A NADH Oxygen Theophylline NAD Water Formaldehyde NADH Oxygen 7- Methylxanthine NAD Water Formaldehyde NADH Oxygen 1- Methylxanthine NAD Water Formaldehyde Water Oxygen 1-Methyluric acid Hydrogen peroxide Oxygen Water 7-Methyluric acid Hydrogen peroxide Oxygen Water 1,3,7- Trimethyluric acid Hydrogen peroxide Oxygen Water 1,7- Dimethyluric acid