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Cytochrome P450 3A28 Leukotriene A-4 hydrolase Leukotriene C4 synthase Glutathione hydrolase 7 Glutathione peroxidase 1 Prostacyclin synthase Prostaglandin- H2 D-isomerase Dihydrodiol dehydrogenase 3 Thromboxane-A synthase Prostaglandin E synthase Prostamide/prostaglandin F synthase Carbonyl reductase [NADPH] 1 Arachidonate 15-lipoxygenase Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Cytochrome P450 2E1 Epoxide hydratase 2 Cytochrome P450 2E1 Epoxide hydratase 2 Arachidonate 15-lipoxygenase Arachidonate 15-lipoxygenase Glutathione peroxidase 1 Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Cytochrome P450 2E1 Epoxide hydratase 2 Cytochrome P450 2E1 Epoxide hydratase 2 Arachidonate 15-lipoxygenase Cytochrome P450 2E1 Arachidonate 15-lipoxygenase Cytochrome P450 2D14 Cytochrome P450 2U1 Cytochrome P450 3A28 Cytochrome P450 2U1 Arachidonate 15-lipoxygenase Cytosolic phospholipase A2 Cytochrome P450 3A28 Cytochrome P450 3A28 20-Hydroxy-leukotriene B4 20-Carboxy-leukotriene B4 Leukotriene B4 NADPH O2 NADP H2O Leukotriene A4 H2O 12-Keto-leukotriene B4 Glutathione Leukotriene C4 H2O Leukotriene D4 L-Glutamic acid 5,6-Epoxytetraene 15(S)-HPETE Glutathione 15(S)-HETE Oxidized glutathione H2O δ-12-Prostaglandin J2 15-Deoxy-d-12,14-PGJ2 6-Keto-prostaglandin F1a 6-Ketoprostaglandin E1 5-HETE 5-KETE Prostaglandin J2 Prostaglandin I2 Prostaglandin D2 Prostaglandin H2 NADPH 11-Epi-PGF2a NADP Thromboxane A2 Prostaglandin E2 Prostaglandin F2a NADPH NADP Prostaglandin A2 Prostaglandin-c2 Thromboxane B2 Prostaglandin B2 11-Dehydro-thromboxane B2 Arachidonic acid O2 O2 11H-14,15-EETA H2O O2 11,14,15-THETA H2O O2 15H-11,12-EETA H2O O2 11,12,15-THETA H2O O2 16(R)-HETE H2O O2 14,15-Epoxy-5,8,11- eicosatrienoic acid H2O H2O 14,15-DiHETrE O2 11,12-Epoxyeicosatrienoic acid H2O H2O 11,12-DiHETrE 5-HPETE O2