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Pyruvate
carboxylase,
mitochondrial
L-lactate
dehydrogenase
A-like 6B
Pyruvate kinase
Phosphoenolpyruvate
carboxykinase,
cytosolic [GTP]
Malate
dehydrogenase,
cytoplasmic
D-2-
hydroxyglutarate
dehydrogenase,
mitochondrial
Hydroxyacylglutathione
hydrolase,
mitochondrial
Lactoylglutathione
lyase
D-3-
phosphoglycerate
dehydrogenase
Aldose
reductase
Aldose
reductase
Malic enzyme
Dihydrolipoyl
dehydrogenase
E3
Dihydrolipoyl
transacetylase
E2
Acetyl-CoA
carboxylase 1
Acetyl-CoA
acetyltransferase,
mitochondrial
Acyl-CoA
thioesterase 12
Acylphosphatase-
1
Aldehyde
dehydrogenase,
mitochondrial
ACSS2 protein
ACSS2 protein
Pyruvate
dehydrogenase
E1
Pyruvic acid
Oxalacetic acid
Phosphoenolpyruvic acid
Pyruvaldehyde
Acetyl-CoA
Acetoacetyl-CoA
ATP
HCO
3
-
ADP
P
i
L-Lactic acid
NAD
NADH
H
+
ATP
ADP
GTP
GDP
CO
2
L-Malic acid
NAD
NADH
H
+
NAD
CO
2
NADH
H
+
D-Lactic acid
H
+
S-Lactoylglutathione
H
2
O
Glutathione
Glutathione
D-Lactaldehyde
NAD
NADH
H
+
Lactaldehyde
NAD
H
+
NADH
Propylene
glycol
NADP
H
+
NADPH
NADP
CO
2
NADPH
Dihydrolipoamide
NAD
Lipoamide
NADH
H
+
S-Acetyldihydrolipoamide-E
Coenzyme A
ATP
HCO
3
-
P
i
ADP
Malonyl-CoA
Coenzyme A
CoA
Acetic acid
H
2
O
Acetylphosphate
H
2
O
P
i
Acetaldehyde
NAD
H
2
O
NADH
H
+
ATP
PP
i
Acetyl adenylate
AMP
PP
i
ATP
CO
2
Biotin
Manganese
Magnesium
Potassium
Manganese
Zinc (II) ion
Zinc (II) ion
Manganese
FAD
Biotin
Manganese
Thiamine
pyrophosphate
Ferricytochrome
c
Ferrocytochrome
c
Nicotinate and
Nicotinamide
Metabolism
Valine,
Leucine, and
Isoleucine
Degradation
Citric Acid
Cycle
Glycolysis
Glycine and
Serine
Metabolism
Propanoate
Metabolism
Ketone Body
Metabolism
Intracellular Space
Mitochondria
Mitochondrial matrix