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Alkaline
phosphatase,
tissue-
nonspecific
isozyme
Pyridoxine-
5'-phosphate
oxidase
Aldehyde
oxidase 1
Pyridoxine-
5'-phosphate
oxidase
Pyridoxal
kinase
Pyridoxal
kinase
Pyridoxal
kinase
Pyridoxine-
5'-phosphate
oxidase
Pyridoxine-
5'-phosphate
oxidase
Alkaline
phosphatase,
tissue-
nonspecific
isozyme
Pyridoxal
phosphate
phosphatase
Pyridoxal
phosphate
phosphatase
Pyridoxal
phosphate
phosphatase
Pyridoxal
5'-phosphate
Pyridoxal
Pyridoxal
Pyridoxamine
Pyridoxamine
Pyridoxal
5'-phosphate
H
2
O
P
i
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
4-Pyridoxic
acid
H
2
O
2
2-Methyl-3-
hydroxy-5-
formylpyridine-
4-carboxylate
3-Hydroxy-2-
methylpyridine-
4,5-
dicarboxylate
Glycolaldehyde
Pyridoxine
O
2
H
2
O
2
P
i
Pyridoxine
5'-phosphate
H
2
O
H
2
O
P
i
P
i
Pyridoxamine
5'-phosphate
H
2
O
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
2
P
i
Pyridoxamine
5'-phosphate
H
2
O
Flavin
Mononucleotide
FAD
Molybdopterin
Flavin
Mononucleotide
Zinc
Zinc
Zinc
Flavin
Mononucleotide
Flavin
Mononucleotide
Magnesium
Magnesium
Magnesium
Valine,
Leucine, and
Isoleucine
Degradation
Gluconeogenesis
Tyrosine
Metabolism
Porphyrin
Metabolism
Sphingolipid
Metabolism
Glycine and
Serine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
Extracellular Space
Intracellular Space
ALPL
PNPO
AOX1
PNPO
PDXK
PDXK
PDXK
PNPO
PNPO
ALPL
PDXP
PDXP
PDXP
Pyridoxal
5'-phosphate
Pyridoxal
Pyridoxal
Pyridoxamine
Pyridoxamine
Pyridoxal
5'-phosphate
Water
Phosphoric acid
Water
Oxygen
Ammonia
Hydrogen
peroxide
Oxygen
Water
4-Pyridoxic
acid
Hydrogen
peroxide
2-Methyl-3-
hydroxy-5-
formylpyridine-
4-carboxylate
3-Hydroxy-2-
methylpyridine-
4,5-
dicarboxylate
Glycolaldehyde
Pyridoxine
Oxygen
Hydrogen
peroxide
Phosphoric acid
Pyridoxine
5'-phosphate
Water
Water
Phosphoric acid
Phosphoric acid
Pyridoxamine
5'-phosphate
Water
Water
Oxygen
Ammonia
Hydrogen
peroxide
Oxygen
Hydrogen
peroxide
Phosphoric acid
Pyridoxamine
5'-phosphate
Water
Valine,
Leucine, and
Isoleucine
Degradation
Gluconeogenesis
Tyrosine
Metabolism
Porphyrin
Metabolism
Sphingolipid
Metabolism
Glycine and
Serine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
ALPL
PNPO
AOX1
PNPO
PDXK
PDXK
PDXK
PNPO
PNPO
ALPL
PDXP
PDXP
PDXP
Pyr-5'P
Pyridox
Pyridox
Pyridoa
Pyridoa
Pyr-5'P
H
2
O
P
i
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
4-Pydox
H
2
O
2
mhfc
3H2M45D
Glyah
Hydoxin
O
2
H
2
O
2
P
i
P5'P
H
2
O
H
2
O
P
i
P
i
Pyrd-5P
H
2
O
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
2
P
i
Pyrd-5P
H
2
O
FlvnMnt
FAD
mlyBdpn
FlvnMnt
Zinc
Zinc
Zinc
FlvnMnt
FlvnMnt
Mg2+
Mg2+
Mg2+
PW000051
PW000152
PW000142
PW000158
PW000148
PW000157
PW000042
Extracellular Space
Intracellular Space