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2-amino-3- ketobutyrate coenzyme A ligase, mitochondrial Serine palmitoyltransferase 1 3- ketodihydrosphingosine reductase Sphingosine kinase 2 Sphingosine- 1-phosphate phosphatase 2 Phospholipid phosphatase 2 SGPL1 protein Sphingolipid delta(4)- desaturase/C4- monooxygenase DES2 SGPL1 protein Sphingosine kinase 2 Sphingosine- 1-phosphate phosphatase 2 Phospholipid phosphatase 2 Alkaline ceramidase Ceramide kinase Phospholipid phosphatase 2 Sphingosine- 1-phosphate phosphatase 2 Sphingomyelin synthase 1 Bis(5'- adenosyl)- triphosphatase ENPP4 UDP- glucuronosyltransferase 3A1 Galactosylceramidase Glucosylceramidase UDP-glucose ceramide glucosyltransferase Unknown Beta-1,4- galactosyltransferase 3 Galactosylceramide sulfotransferase Arylsulfatase A Alpha-N- acetylgalactosaminidase Galactosylceramide sulfotransferase Sialidase-3 ACER3 protein L-Serine Palmityl-CoA 3-Dehydrosphinganine Sphinganine NADPH NADP ATP ADP Sphinganine 1-phosphate ADP ATP Pi O- Phosphoethanolamine Dihydroceramide Ceramide (d18:1/18:0) Sphingosine 1-phosphate Sphingosine ATP ADP ADP ATP Pi ATP CerP(d18:1/12:0) ADP Pi SM(d18:1/18:0) Galactosylceramide (d18:1/16:0) Glucosylceramide Lactosylceramide (d18:1/12:0) Phosphoadenosine phosphosulfate 3-O-Sulfogalactosylceramide (d18:1/24:0) Adenosine 3',5'- diphosphate H2O Sulfate D-Galactose Galabiosylceramide (d18:1/22:0) Phosphoadenosine phosphosulfate Adenosine 3',5'- diphosphate N-acetylneuraminyl- Galactosylceramide Sphinganine Pyridoxal 5'-phosphate Magnesium Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Magnesium Calcium Magnesium Magnesium Zinc Calcium Galabiosylceramide- sulfate Glycine and Serine Metabolism Intracellular space Endoplasmic Reticulum Golgi complex Golgi complex Lysosome Lysosome Endoplasmic Reticulum