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Beta-Ala-His dipeptidase Carnosine synthase 1 Protein arginine N- methyltransferase 3 Histidine decarboxylase Histamine N- methyltransferase Amine oxidase [flavin- containing] A Aldehyde dehydrogenase, dimeric NADP-preferring Aldehyde dehydrogenase, mitochondrial Histidine ammonia-lyase Urocanate hydratase 1 Amidohydrolase domain-containing 1 Formimidoyltransferase- cyclodeaminase Amiloride- sensitive amine oxidase [copper- containing] Unknown Carnosine synthase 1 Cytosolic non-specific dipeptidase Histidyl-tRNA synthetase 2, mitochondrial Histidyl-tRNA synthetase 2-like L-Glutamic acid Carnosine H2O β-Alanine L-Histidine ATP β-Alanine ADP Pi S- Adenosylmethionine 3-Methylhistidine S- Adenosylhomocysteine Histamine CO2 S- Adenosylmethionine S- Adenosylhomocysteine 1-Methylhistamine H2O O2 Methylimidazole acetaldehyde NH3 H2O2 NADP H2O Methylimidazoleacetic acid NADPH H+ Imidazole-4- acetaldehyde NAD H2O Imidazoleacetic acid NADH H+ NH3 Urocanic acid 4-Imidazolone- 5-propionic acid H2O H2O Formiminoglutamic acid Tetrahydrofolic acid 5- Formiminotetrahydrofolic acid H2O O2 NH3 H2O2 S- Adenosylmethionine S- Adenosylhomocysteine Anserine ATP 1-Methylhistidine β-Alanine ADP Pi H2O β-Alanine ATP AMP PPi ATP AMP PPi Zinc (II) ion Manganese Pyridoxal 5'-phosphate FAD NAD Zinc (II) ion Pyridoxal 5'-phosphate Copper Calcium Topaquinone tRNA(His) L- Histidyl- tRNA(His) tRNA(His) Glutamate Metabolism Manganese Manganese Intracellular Space Extracellular Space
Cndp1 Carns1 Prmt3 Hdc Hnmt Maoa Aldh3a1 Aldh2 Hal Uroc1 Amdhd1 Ftcd Aoc1 Unknown Carns1 Cndp2 Hars2 Hars2 L-Glutamic acid Carnosine Water β-Alanine L-Histidine Adenosine triphosphate β-Alanine Adenosine diphosphate Phosphate S- Adenosylmethionine 3-Methylhistidine S- Adenosylhomocysteine Histamine Carbon dioxide S- Adenosylmethionine S- Adenosylhomocysteine 1-Methylhistamine Water Oxygen Methylimidazole acetaldehyde Ammonia Hydrogen peroxide NADP Water Methylimidazoleacetic acid NADPH Hydrogen Ion Imidazole-4- acetaldehyde NAD Water Imidazoleacetic acid NADH Hydrogen Ion Ammonia Urocanic acid 4-Imidazolone- 5-propionic acid Water Water Formiminoglutamic acid Tetrahydrofolic acid 5- Formiminotetrahydrofolic acid Water Oxygen Ammonia Hydrogen peroxide S- Adenosylmethionine S- Adenosylhomocysteine Anserine Adenosine triphosphate 1-Methylhistidine β-Alanine Adenosine diphosphate Phosphate Water β-Alanine Adenosine triphosphate Adenosine monophosphate Pyrophosphate Adenosine triphosphate Adenosine monophosphate Pyrophosphate tRNA(His) L- Histidyl- tRNA(His) tRNA(His) Glutamate Metabolism
Cndp1 Carns1 Prmt3 Hdc Hnmt Maoa Aldh3a1 Aldh2 Hal Uroc1 Amdhd1 Ftcd Aoc1 Carns1 Cndp2 Hars2 Hars2 Glu Carnosi H2O b-Ala His ATP b-Ala ADP Pi SAMe 3-Mhis SAH Hsm CO2 SAMe SAH 1Mhis H2O O2 MetmAch NH3 H2O2 NADP H2O Mldzaa NADPH H+ Imd4aca NAD H2O Imaa NADH H+ NH3 Urocana 4Im-5pa H2O H2O FormGlu THFA 5-FTHA H2O O2 NH3 H2O2 SAMe SAH Anserin ATP 1-Mhis b-Ala ADP Pi H2O b-Ala ATP AMP PPi ATP AMP PPi Zinc Mn2+ Pyr-5'P FAD NAD Zinc Pyr-5'P Cu Ca2+ TopQne TRNAHIS LHTH TRNAHIS PW000003 Mn2+ Mn2+ Intracellular Space Extracellular Space
Cndp1 Carns1 Prmt3 Hdc Hnmt Maoa Aldh3a1 Aldh2 Hal Uroc1 Amdhd1 Ftcd Aoc1 Carns1 Cndp2 Hars2 Hars2 Glu Carnosi H2O b-Ala His ATP b-Ala ADP Pi SAMe 3-Mhis SAH Hsm CO2 SAMe SAH 1Mhis H2O O2 MetmAch NH3 H2O2 NADP H2O Mldzaa NADPH H+ Imd4aca NAD H2O Imaa NADH H+ NH3 Urocana 4Im-5pa H2O H2O FormGlu THFA 5-FTHA H2O O2 NH3 H2O2 SAMe SAH Anserin ATP 1-Mhis b-Ala ADP Pi H2O b-Ala ATP AMP Ppi ATP AMP Ppi TRNAHIS LHTH TRNAHIS PW000003