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GTP
cyclohydrolase
GTP
cyclohydrolase
GTP
cyclohydrolase
GTP
cyclohydrolase
6-pyruvoyl
tetrahydrobiopterin
synthase
CG12117-PA
CG12117-PA
CG6084, isoform
D
Carbonyl
reductase,
isoform A
CG12117-PA
Carbonyl
reductase,
isoform A
CG12117-PA
Dihydrofolate
reductase
Dihydropteridine
reductase,
isoform C
CG12117-PA
Guanosine triphosphate
Formamidopyrimidine nucleoside
triphosphate
H
2
O
2,5-Diaminopyrimidine
nucleoside triphosphate
Formic acid
H
2
O
Formic acid
2,5-Diamino-6-(5'-
triphosphoryl-3',4'-
trihydroxy-2'-oxopentyl)-
amino-4-oxopyrimidine
Dihydroneopterin triphosphate
H
2
O
Dyspropterin
PPPi
NADP
NADPH
1-hydroxy-2-Oxopropyl
tetrahydropterin
NADP
6-Lactoyltetrahydropterin
NADPH
NADP
NADPH
Sepiapterin
NADPH
7,8-Dihydroneopterin
NADP
NADP
NADPH
NADP
Tetrahydrobiopterin
NADPH
NADPH
NADP
H
2
O
Neopterin
NADP
Dihydrobiopterin
NADPH
NAD
NADH
Zinc
Zinc
Zinc
Zinc
Zinc
Purine
Metabolism
Intracellular space
Pu
Pu
Pu
Pu
pr
CG12117
CG12117
34F4T
CG11200
CG12117
CG11200
CG12117
Dhfr
Dhpr
CG12117
Guanosine
triphosphate
Formamidopyrimidine
nucleoside
triphosphate
Water
2,5-
Diaminopyrimidine
nucleoside
triphosphate
Formic acid
Water
Formic acid
2,5-Diamino-
6-(5'-
triphosphoryl-
3',4'-
trihydroxy- 2'-
oxopentyl)-
amino-4-
oxopyrimidine
Dihydroneopterin
triphosphate
Water
Dyspropterin
PPPi
NADP
NADPH
1-hydroxy-2-
Oxopropyl
tetrahydropterin
NADP
6-
Lactoyltetrahydropterin
NADPH
NADP
NADPH
Sepiapterin
NADPH
7,8-
Dihydroneopterin
NADP
NADP
NADPH
NADP
Tetrahydrobiopterin
NADPH
NADPH
NADP
Water
Neopterin
NADP
Dihydrobiopterin
NADPH
NAD
NADH
Purine
Metabolism
Pu
Pu